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1.A.81.1.1
Low affinity Ca2+ influx system, Fig1p (Factor induced gene 1) (Muller et al., 2003; Ren et al., 2006) (298 aas; 4 TMSs).  Involved in low affinity Ca2 influx during mating; required for membrane fusion during mating (Muller et al. 2003).

Accession Number:P38224
Protein Name:Fig1p
Length:298
Molecular Weight:33776.00
Species:Saccharomyces cerevisiae (Baker's yeast) [4932]
Number of TMSs:4
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate Ca2+

Cross database links:

Genevestigator: P38224
eggNOG: fuNOG10002
DIP: DIP-1347N
RefSeq: NP_009596.1   
Entrez Gene ID: 852328   
KEGG: sce:YBR040W   

Gene Ontology

GO:0009277 C:fungal-type cell wall
GO:0016021 C:integral to membrane
GO:0043332 C:mating projection tip
GO:0005515 F:protein binding
GO:0000753 P:cell morphogenesis involved in conjugation ...
GO:0000755 P:cytogamy

References (4)

[1] “Differential evolution of the Saccharomyces cerevisiae DUP240 paralogs and implication of recombination in phylogeny.”  Leh-Louis V.et.al.   15087486
[2] “Complete DNA sequence of yeast chromosome II.”  Feldmann H.et.al.   7813418
[3] “Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae.”  Hu Y.et.al.   17322287
[4] “Large-scale phosphorylation analysis of alpha-factor-arrested Saccharomyces cerevisiae.”  Li X.et.al.   17330950

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MVAISMIWFF TKRMPRIFAL AFNLISIFLL IFLLIGCYNP SNQSTFLVKY KFDDNSPFYT 
61:	IIEKSYEKSN TTLGLEEVII RSGYMGVCID NIPSQYSSYN NMTTFSNSIC YARKNLSSVP 
121:	LYRDLEIQLS NIASSSSKTQ SSVVLNILKL AQLTSVNVIH PYVLMATVIL TILMFLFILY 
181:	VTVPKLPFKL AVNKFLLLLS STIVLTWGIG AMWTHVGINA SYRLVPSSSM NIITVKKGKK 
241:	AAVMAWFSFA FLLLDSVVLW LIFLRDRKSL KDEIDNVPCA QNRYNNYSSD SSTLHSKV