Echovirus E30 polyprotein (128 aas; fragment). An intracellular (endomembrane) pore-forming peptide toxin which induces membrane permeability due to two consecutive hydrophobic segments that may form an α-helix-turn-α-helix hairpin membrane anchor that provides the basis for oligomeric pore formation (Sánchez-Martínez et al. 2012). This protein is derived from the Coxsackle virus B2 protein of 2187 aas (Q9YLG5) and may interact with a Ryanodine receptor (Schilling et al. 2013).
|Species:||Echovirus E30  |
1: IVGFADVRDL LWLEDDAMEQ GVKDYVEQLG NAFGSGFTNQ ICEQVNLLKE SLIGQDSILE
61: KSLKALVKII SALVIVVRNH DDLITVTATL ALIGCTTSPW RWLKRKVSQY YGIPMAERQN