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1.A.85.1.3
Echovirus E30 polyprotein (128 aas; fragment).  An intracellular (endomembrane) pore-forming peptide toxin which induces membrane permeability due to two consecutive hydrophobic segments that may form an α-helix-turn-α-helix hairpin membrane anchor that provides the basis for oligomeric pore formation (Sánchez-Martínez et al. 2012).  This protein is derived from the Coxsackle virus B2 protein of 2187 aas (Q9YLG5) and may interact with a Ryanodine receptor (Schilling et al. 2013).

Accession Number:Q91QV6
Protein Name:Polyprotein
Length:128
Molecular Weight:14414.00
Species:Echovirus E30 [41846]
Substrate small molecules

Cross database links:

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	IVGFADVRDL LWLEDDAMEQ GVKDYVEQLG NAFGSGFTNQ ICEQVNLLKE SLIGQDSILE 
61:	KSLKALVKII SALVIVVRNH DDLITVTATL ALIGCTTSPW RWLKRKVSQY YGIPMAERQN 
121:	NGWLKKFT