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1.A.9.1.14
Acetylcholine receptor with two subunits, α and β, Deg-3 (564 aas)and Acr-4 (548 aas).  Subunits of the non-synaptic neuronal AChR, which may play a role in chemotaxis towards choline. After binding choline or acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane (Treinin et al. 1998; Yassin et al. 2001).

Accession Number:P54244
Protein Name:Acetylcholine receptor subunit alpha-type deg-3
Length:564
Molecular Weight:64927.00
Species:Caenorhabditis elegans [6239]
Number of TMSs:5
Location1 / Topology2 / Orientation3: Cell junction1 / Multi-pass membrane protein2
Substrate

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  • 2° Structure (Network Protein Sequence Analysis)

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MTLKIRTIII LFCVISVTTT SQSLNATLKT FDPRLLNSTA DRDIAMKNVP LVRLTRHLLS 
61:	PERYDVRVRP ILDHKKSLKV HISISLYQII EVDEPSQNIK LNVWMIQKWR DEYLDWNPNE 
121:	YGMINSTIIP FHHLWIPDTY LYNSVKMSRD ETERYMNIQA TSNYWKGEKG AELSFLYPAI 
181:	YTITCRLNIR FFPYDRQNCT LTISSWTNSK SALDYYADTE VSMQSFIPNE EWQVKSFKIH 
241:	RHEYKYACCA EPWVILQASL VIQRKPLYYL VNLIIPTSII TLVAITGFFT PASTDDDRTE 
301:	KINLGITTLL AMSILMLMVS DQMPTTSEFV PLIAWFYLSI IIIISIGTFL TSVVLSVQGR 
361:	RQYGRNPPQF IRYIFFVLLP QVLLLNVPPP LQTLWGELDD DPLNVRRRKK SHYLSRNVNN 
421:	GSTKMASPMS TLRVPQSAGS VSEKRQSFQM IDVTSPNSPN TARSRAPSLA PSTAKATMWE 
481:	GTMSALAGTN TQLRRTSNVF NKEVDEMRRK RQCSLEWEFL ATVLDRFLLI VFVGAVVIVT 
541:	AGLILVGRMA QYSYDHPDDR FFNV