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1.A.9.1.5
Acetylcholine receptor subunit alpha-type acr-5

Accession Number:P54246
Protein Name:Acetylcholine receptor subunit alpha-type acr-5
Length:598
Molecular Weight:70280.00
Species:Caenorhabditis elegans [6239]
Number of TMSs:5
Location1 / Topology2 / Orientation3: Cell junction1 / Multi-pass membrane protein2
Substrate ions

Cross database links:

eggNOG: NOG300124
HEGENOM: HOG000019549
Entrez Gene ID: 191596   
Pfam: PF02931    PF02932   
KEGG: cel:K03F8.2   

Gene Ontology

GO:0030054 C:cell junction
GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0045211 C:postsynaptic membrane
GO:0005230 F:extracellular ligand-gated ion channel activity
GO:0004872 F:receptor activity

References (1)

[1] “Genome sequence of the nematode C. elegans: a platform for investigating biology.”  The C. elegans sequencing consortiumet.al.   9851916

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MLPNIILILL IRYCSCGAGS RVYEKYGKQV QLSPATTSSY REWYDSNREH STRNNTNVDD 
61:	FQTQLKKSLE NTTAAYNATF MQELIEERQR YLEKLNEGQF INDQRRLVEE LLDPNYYEKT 
121:	VHPKRDYTRP TRVNLSMSLY QILDVDEHMQ SIEVNVWMVQ HWYDEFLDWN PVDYGMINRT 
181:	IVPYHQIWIP DTYLYNSEEL EQKKTESLMN AQLETGHWNQ KKDGAKVQLM FPAIYKLSCR 
241:	MDVRWFPYDR QNYKTSFKPM KLLQQTIDYW PLSSTVNLGN MARNDEWEVI SFEFVRVEET 
301:	FKCCTAPWVM LYAHLVIRRK PLYYMINLVV PTSIITIVAV TGFFTPTSSS SERDEKLYLG 
361:	INTLLTMSVM MLMVCNQMPS TSTYVPLMSW YYIGIIMVIV VGTFLATGVL AIHGQKHYNK 
421:	PISDRIRKLI YNPVVEFFIL SPPTSLIDLW TEFGVISEQR HSTHLDPLLL QHMDPISHTT 
481:	RADPQHFFGS ISSQMCDLQS TYSYTARLAT ITRQYTQHAK MKALRKNQYR MSMDTSQARG 
541:	VKKQKMQRRC SLEWEFLANV LDRILLTIFC GFTFAVFIIL IGFDSFFTFH TDSPPKTM