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1.A.9.5.9
GabaA1 receptor of 459 aas and 4 TMSs.  87% identical to the human homologue (TC# 1.A.9.5.4). Insecticides, abamectin, dieldrin, fluralaner and fipronil strongly inhibited GABA-induced inward current >50% at 10-6 M, while alpha-endosulfan, flufiprole and ethiprole inhibited <50% (Huang et al. 2018).

Accession Number:Q08BJ3
Protein Name:Gabra1 protein
Length:459
Molecular Weight:51645.00
Species:Danio rerio (Zebrafish) [7955]
Number of TMSs:4
Substrate

Cross database links:

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MMWGGRGAAW LWIWACLLVT NALAGKSSSQ NADEQKDNTT VFTRILDSLL DGYDNRLRPG 
61:	LGERVTEVKT DIFVTSIGPV SDHDMEYTID VFFRQSWKDE RLKFKGPMAV LRLNNLMASK 
121:	IWTPDTFFHN GKKSVAHNMT MPNKLLRITE EGTLLYTMRL TVRAECPMHL EDFPMDAHAC 
181:	PLKFGSYAYT RAEVVYVWTR GAAQSVVVAD DGSRLNQYDL MGQSVDSGVV QSSTGEYVVM 
241:	TTHFHLKRKI GYFVIQTYLP CIMTVILSQV SFWLNRESVP ARTVFGVTTV LTMTTLSISA 
301:	RNSLPKVAYA TAMDWFIAVC YAFVFSALIE FATVNYFTKR GYAWDGKSVV PEKQKKKKES 
361:	LLKKNNTYTA ATATAFAPNI ARDPGLATIA KSAPPPPTEP KEEPKPKPPE AKKTFNSVSK 
421:	IDRIARIAFP LLFGTFNLVY WATYLNKKPK LQGMNLQPH