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1.A.9.6.1
Homomeric serotonin (5-HT)-gated chloride channel, (controlling locomotion) MOD-1 (Menard et al., 2005)

Accession Number:Q9GQ00
Protein Name:MOD-1 aka K06C4.6
Length:489
Molecular Weight:56143.00
Species:Caenorhabditis elegans [6239]
Number of TMSs:4
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate Cl-

Cross database links:

HEGENOM: HBG506497
RefSeq: NP_741580.1   
Entrez Gene ID: 179269   
Pfam: PF02931    PF02932   

Gene Ontology

GO:0030054 C:cell junction
GO:0016021 C:integral to membrane
GO:0045211 C:postsynaptic membrane
GO:0005230 F:extracellular ligand-gated ion channel acti...
GO:0006811 P:ion transport

References (2)

[1] “MOD-1 is a serotonin-gated chloride channel that modulates locomotory behaviour in C. elegans.”  Ranganathan R.et.al.   11100728
[2] “Genome sequence of the nematode C. elegans: a platform for investigating biology.”  The C. elegans sequencing consortiumet.al.   9851916

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
Window Size: Angle:  
FASTA formatted sequence
1:	MKFIPEITLL LLLFVHSTQA KGKRRKCPEG AWSEGKIMNT IMSNYTKMLP DAEDSVQVNI 
61:	EIHVQDMGSL NEISSDFEID ILFTQLWHDS ALSFAHLPAC KRNITMETRL LPKIWSPNTC 
121:	MINSKRTTVH ASPSENVMVI LYENGTVWIN HRLSVKSPCN LDLRQFPFDT QTCILIFESY 
181:	SHNSEEVELH WMEEAVTLMK PIQLPDFDMV HYSTKKETLL YPNGYWDQLQ VTFTFKRRYG 
241:	FYIIQAYVPT YLTIIVSWVS FCMEPKALPA RTTVGISSLL ALTFQFGNIL KNLPRVSYVK 
301:	AMDVWMLGCI SFVFGTMVEL AFVCYISRCQ NSVRNAERRR ERMRNSQVWA NGSCRTRSNG 
361:	YANGGSVISH YHPTSNGNGN NNRHDTPQVT GRGSLHRNGP PSPLNLQMTT FDSEIPLTFD 
421:	QLPVSMESDR PLIEEMRSTS PPPPSGCLAR FHPEAVDKFS IVAFPLAFTM FNLVYWWHYL 
481:	SQTFDQNYQ