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1.A.9.6.3
The high affinity tyramine (amine-gated) chloride channel receptor, Lgc-55 (Ringstad et al., 2009).  Activated by amphetamines (Safratowich et al. 2013).

Accession Number:Q9TVI7
Protein Name:Protein Y113G7A.5, partially confirmed by transcript evidence
Length:538
Molecular Weight:62081.00
Species:Caenorhabditis elegans [6239]
Number of TMSs:4
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate Cl-

Cross database links:

eggNOG: meNOG05726
HEGENOM: HBG506497
RefSeq: NP_507870.2   
Entrez Gene ID: 180312   
Pfam: PF02931    PF02932   
KEGG: cel:Y113G7A.5   

Gene Ontology

GO:0030054 C:cell junction
GO:0016021 C:integral to membrane
GO:0045211 C:postsynaptic membrane
GO:0005230 F:extracellular ligand-gated ion channel acti...
GO:0009792 P:embryonic development ending in birth or eg...
GO:0006811 P:ion transport

References (1)

[1] “Genome sequence of the nematode C. elegans: a platform for investigating biology.”  The C. elegans sequencing consortiumet.al.   9851916

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MVFSFILTFT ISVVAAFDDE CIKCDLRSSY CKTWENSTQS CECRDGFARI SNGSCAMVSD 
61:	LARGGLGLSQ DSEEDEPFCV LGQAEKAATR ILTELLSKYD RNLVPKMKGV DVDVELLIQR 
121:	VSEISEIQSS STMHILFSQI WHDPGLSFEH EEGAHCLTNL SLSHRMVDNI WLPNVCIVNS 
181:	KGSAIHKSPT PNIFLAIFPN GTVWMNYRVV VESPCEMDFS FFPMDRVMCT TIFESYAFNV 
241:	GKVRLHWKRQ GQPVEFIDDV KLPDFHMTKF VHEKATFIYP AGVWDQLNIK LLFRRSYGFY 
301:	ILQIYLPTYC MVLISWISFW LDRRSLPARV TLGVSSLMAL TLQYSNVSRS LPKVSYVKGL 
361:	DLFMFGCIVY IFLSIVELAV VGSLEQRKQQ RTNADGDFLS DDDIKKNIFQ RTFSTKSFKS 
421:	GYGARHHQFS ECASPEDGGE WPKTRTEWAE RTYVECPEPE PPESNRHPEV ENDSNNKMLV 
481:	LVRQRRASRK RRKRLMSGKL FQRWTAEDMD RFCQKLFPIT FTFCNLIYWM YYTAKSKD