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1.A.9.6.4
The low-affinity serotonin receptor, Lgc-40; also gated by choline and acetylcholine (Ringstad et al., 2009).

Accession Number:Q22741
Protein Name:Putative uncharacterized protein
Length:494
Molecular Weight:57005.00
Species:Caenorhabditis elegans [6239]
Number of TMSs:4
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate ions

Cross database links:

eggNOG: meNOG04494
HEGENOM: HBG506497
RefSeq: NP_508428.2   
Entrez Gene ID: 188854   
Pfam: PF02931    PF02932   
KEGG: cel:T24D8.1   

Gene Ontology

GO:0030054 C:cell junction
GO:0016021 C:integral to membrane
GO:0045211 C:postsynaptic membrane
GO:0005230 F:extracellular ligand-gated ion channel acti...
GO:0006811 P:ion transport

References (1)

[1] “Genome sequence of the nematode C. elegans: a platform for investigating biology.”  The C. elegans sequencing consortiumet.al.   9851916

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MKLHTMIRFL LSVCCIVNVF ESADLAFIPL TKAFLDKLKN ETLYNRFATP TQYDGVPTNV 
61:	TLSMFIEGMS SFSAQTMDYH LDVYFQEEWY DHRLAHNASA PILVRDLTVF KMMWHPDVYF 
121:	ANARSAAFQD ITDDNFLVWV YPNGRVWYDA RISIVSSCNM DLWKYPLDSQ ECALRILSYA 
181:	YPMTVLRLLW SEKEDVPAID RNPDITMPDM SLKHIRTGYC NGTYATGEWS CMTAIFYVER 
241:	EMMHHVMQTY VPTALIVVIS WFNFWLEIDS APARVSLSIT TLLTISTQAN AVKLALPEVS 
301:	YMKAIDVWMG SCMAFVFGVM IEFTICHYAK NLEMLRGDGQ PSLIVDTALS TLFGAARDID 
361:	DLVRKVATLN EEEGVRGDGE QHIALNMLNP EEPRLRSLNQ NNDVTANGTR YFVGAERMKR 
421:	KRSKASLSRL RQQVASMRHA TIDVSRRAFN WTRALRNLRG RRVAQRIDER CRIVFPMIFL 
481:	LFNVAYWSFY LVFN