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1.B.1.1.20
Outer membrane porin 1, OmpPst1 or Omp-Pst1.  Transports beta lactams with decreased efficiency in the order of ertapenem > cefepime > cefoxitin (Tran et al. 2010).  93% identical in sequence to 1.B.1.1.11. Voltage-gating of this porin and porin 2 (TC# 1.B.1.1.24) from the same organism have been analyzed (Song et al. 2015). Facing channels are open in any two adjacent porin structures, suggesting that dimers and trimers not only promote cell-to-cell contact but also contribute to intercellular communication (El-Khatib et al. 2018).

Accession Number:J9VK71
Protein Name:Porin
Length:371
Molecular Weight:40894.00
Species:Providencia stuartii [588]
Number of TMSs:1
Location1 / Topology2 / Orientation3: Cell outer membrane1 / Multi-pass membrane protein2
Substrate ertapenem, Cefepime, Cefoxitin

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  • 2° Structure (Network Protein Sequence Analysis)

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MMKRNILAMV IPALLAAGAA NAAEVYNKDG NKLDVYGKVD VRHYFADADK GKKSEDGDDS 
61:	RVRLGVKGDT QITDQLTGFG RFEWETKTNK AENEGENKNR LAYAGLKFAD FGSIDYGRNY 
121:	GVVYDTNAWT DVFPLWGADT MAQSDNFMTS RNRNLLTYRN NNAFGYVDGL SFALQYQGKN 
181:	GDNNKSSAGE AAKDNGDGYG FSAAYDLGWG VSLGGGYSNS SRTPNQQHNT TAGGQKAQAW 
241:	NVGGKFDANN VYLAAMYGQT LNTTRYGSKD SIANKTENVE LVAQYLFDFG LKPSIGYNQS 
301:	KGKDLGRAYN GKTYNNQDLV KYISVGSYYY FNKNMSAVVD YKINLLKDND FTRENGINTD 
361:	NVLGLGLVYQ F