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1.B.1.4.3
Porin of 38 KDa,Omp38 in Burkholderia pseudomallei, the causative agent of melioidosis, an infectious disease of animals and humans. MDR can be due to mutations in Omp38.  Ion current blockages of reconstituted Omp38 by seven antimicrobial agents occurred in a concentration-dependent manner with the translocation on-rate following the order: norfloxacin>ertapenem>ceftazidime>cefepime>imipenem>meropenem>penicillin G (Suginta et al. 2011).  Also allows transport of neutral sugars and numerous antimicrobial agents including cephalosporin and carbapenem (Aunkham et al. 2014).

Accession Number:Q7WZL2
Protein Name:Outer membrane porin
Length:374
Molecular Weight:39132.00
Species:Burkholderia pseudomallei [28450]
Number of TMSs:1
Substrate norfloxacin, ertapenem, Ceftazidime, Cefepime, Imipenem, Meropenem, Pencillin G

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  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MNKTLIVAAV AASFATVAHA QSSVTLYGVL DAGITYQSNV ATPSGSGKSL WSVGAGVDQS 
61:	RFGLRGSEDL GGGLKAIFTL ESGFNIGNGR FNNGGGMFNR QAFVGLSSNY GTVTLGRQYD 
121:	ATQDYLSPLS ATGTWGGTYF AHPLNNDRLN TNGDVAVNNT VKFTSANYAG LQFGGTYSFS 
181:	NNSQFANNRA YSAGASYQFQ GLKVGAAYSQ ANNAGANTTG ATDPLTGFNI GGTNAASIQG 
241:	RSRVYGAGAS YAYGPLQGGL LWTQSRLDNL ANGAPTIRAD NYEANVKYNL TPALGLGVAY 
301:	TYTNAKANGE STHWNQVGVQ ADYALSKRTD VYAQAVYQRS SKNANASIYN GDLSTPFSTS 
361:	INQTAATVGL RHRF