TCDB is operated by the Saier Lab Bioinformatics Group
TCIDNameDomainKingdom/PhylumProtein(s)
*1.B.11.1.1









Type κ fimbrial usher, FacD
Bacteria
Proteobacteria
FacD of E. coli (P06970)
*1.B.11.1.2









Type κ fimbrial usher, AfrB
Bacteria
Proteobacteria
AfrB of E. coli (Q07686)
*1.B.11.2.1









Type π fimbrial usher, PapC. The crystal structure of the PapC usher translocation domain has been solved (Daniels and Normark, 2008; Remaut et al., 2008).  The crystal structure of the full-length PapC usher in complex with its cognate PapDG chaperone-subunit complex in a pre-activation state has been solved.  This elucidated the molecular details of how the usher is specifically engaged by allosteric interactions with its substrate, preceding activation, and how the usher facilitates the transfer of subunits from the amino-terminal periplasmic domain to the CTDs during pilus assembly (Omattage et al. 2018).

Bacteria
Proteobacteria
PapC of E. coli (P07110)
*1.B.11.2.2









Uncharacterized outer membrane usher protein YbgQ

Bacteria
Proteobacteria
YbgQ of Escherichia coli
*1.B.11.3.1









Type γ fimbrial usher, FimC
Bacteria
Proteobacteria
FimC of Bordetella pertussis (P33410)
*1.B.11.3.2









The outer membrane usher protein, MrkC precursor (for type III fimbriae) (Burmolle et al., 2008)
Bacteria
Proteobacteria
MrkC precursor of Bordetella pertussis (P21647)
*1.B.11.3.3









Type γ4 fimbrial usher, HtrE or EcpC.  Functions with EcpD to assemble the E. coli common pilus, and extracellular fiber-like structure that plays a role in early biofilm formation and host cell recognition (Garnett et al. 2012).

Bacteria
Proteobacteria
HtrE of E. coli (P33129)
*1.B.11.3.4









Type γ3 fimbrial usher, CssD
Bacteria
Proteobacteria
CssD of E. coli (P53513)
*1.B.11.3.5









Type γ1 fimbrial usher, YcbS
Bacteria
Proteobacteria
YcbS of E. coli (Q8CVM4)
*1.B.11.3.6









Type γ2 fimbrial usher, YraJ
Bacteria
Proteobacteria
YraJ of E. coli (P42915)
*1.B.11.3.7









Usher protein, CupB3 (POTRA domain containing P-usher) [Dual function in secreting fimbril subunits and cell surface adhesin, CupB5 (Q9HWU6) which is homologous to members of the AT1 and AT2 families (1.B.12 and 1.B.40)] (Ruer et al., 2008).
Bacteria
Proteobacteria
CupB3 Usher of Pseudomonas aeruginosa (Q9HWU4)
*1.B.11.3.8









Usher, Caf1A, important for F1 antigen assembly

Bacteria
Proteobacteria
Caf1A of Yersinia pestis (P26949)
*1.B.11.3.9









Fimbial usher protein, FimD

Bacteria
Proteobacteria
FimD of E. coli (P30130)
*1.B.11.3.10









Outer membrane usher protein FasD

Bacteria
Proteobacteria
FasD of E. coli
*1.B.11.3.11









Fimbrial usher, YehB of 826 aas.

Bacteria
Proteobacteria
YehB of E. coli
*1.B.11.4.1









Type α fimbrial usher, CfaC
Bacteria
Proteobacteria
CfaC of E. coli (P25733)
*1.B.11.5.1









Type β fimbrial usher, YhcD
Bacteria
Proteobacteria
YhcD of E. coli (P45420)
*1.B.11.6.1









Type σ fimbrial usher, CsuD
Bacteria
Proteobacteria
CsuD of Acinetobacter baumannii (Q6XBY3)
*1.B.11.6.2









Fimbrial usher protein

Bacteria
Proteobacteria
FUP of Myxococcus xanthus
*1.B.11.6.3









Fimbrial usher, PapC

Bacteria
Spirochaetes
PapC homologue of Spirochaeta africana
*1.B.11.6.4









Fimbrial usher protein of 892 aas (Nuccio and Bäumler 2007).

Bacteria
Cyanobacteria
Fimbrial usher protein of Synechocystis sp.
*1.B.11.7.1









Fimbrial O.M. usher protein (760aas)
Bacteria
Proteobacteria
Usher protein of Burkholderia multivorans (A9AQJ0)
*1.B.11.8.1









Fimbrial usher protein of 729 aas (Nuccio and Bäumler, 2007). Note: Deinococcus radiodurans has an envelope with two membranes; the outer membrane lacks lipopolysaccharide.

Bacteria
Deinococcus-Thermus
Fimbrial usher protein of Deinococcus radiodurans