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1.B.11.3.3
Type γ4 fimbrial usher, HtrE or EcpC.  Functions with EcpD to assemble the E. coli common pilus, and extracellular fiber-like structure that plays a role in early biofilm formation and host cell recognition (Garnett et al. 2012).

Accession Number:P33129
Protein Name:Outer membrane usher protein htrE
Length:865
Molecular Weight:95499.00
Species:Escherichia coli (strain K12) [83333]
Location1 / Topology2 / Orientation3: Cell outer membrane1 / Multi-pass membrane protein2
Substrate Fimbrial subunits

Cross database links:

Genevestigator: P33129
EchoBASE: EB1915
EcoGene: EG11972
eggNOG: COG3188
HEGENOM: HBG511492
DIP: DIP-9953N
RefSeq: AP_000800.1    NP_414681.1   
Entrez Gene ID: 944819   
Pfam: PF00577   
BioCyc: EcoCyc:EG11972-MONOMER    ECOL168927:B0139-MONOMER   
KEGG: ecj:JW0135    eco:b0139   

Gene Ontology

GO:0009279 C:cell outer membrane
GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0005215 F:transporter activity
GO:0006950 P:response to stress
GO:0006810 P:transport

References (4)

[1] “Identification and transcriptional analysis of the Escherichia coli htrE operon which is homologous to pap and related pilin operons.”  Raina S.et.al.   8102362
[2] “Systematic sequencing of the Escherichia coli genome: analysis of the 2.4-4.1 min (110,917-193,643 bp) region.”  Fujita N.et.al.   8202364
[3] “The complete genome sequence of Escherichia coli K-12.”  Blattner F.R.et.al.   9278503
[4] “Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110.”  Hayashi K.et.al.   16738553

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MTIEYTKNYH HLTRIATFCA LLYCNTAFSA ELVEYDHTFL MGQNASNIDL SRYSEGNPAI 
61:	PGVYDVSVYV NDQPIINQSI TFVAIEGKKN AQACITLKNL LQFHINSPDI NNEKAVLLAR 
121:	DETLGNCLNL TEIIPQASVR YDVNDQRLDI DVPQAWVMKN YQNYVDPSLW ENGINAAMLS 
181:	YNLNGYHSET PGRKNESIYA AFNGGMNLGA WRLRASGNYN WMTDSGSNYD FKNRYVQRDI 
241:	ASLRSQLILG ESYTTGETFD SVSIRGIRLY SDSRMLPPTL ASFAPIIHGV ANTNAKVTIT 
301:	QGGYKIYETT VPPGAFVIDD LSPSGYGSDL IVTIEESDGS KRTFSQPFSS VVQMLRPGVG 
361:	RWDISGGQVL KDDIQDEPNL FQASYYYGLN NYLTGYTGIQ ITDNNYTAGL LGLGLNTSVG 
421:	AFSFDVTHSN VRIPDDKTYQ GQSYRVSWNK LFEETSTSLN IAAYRYSTQN YLGLNDALTL 
481:	IDEVKHPEQD LEPKSMRNYS RMKNQVTVSI NQPLKFEKKD YGSFYLSGSW SDYWASGQNR 
541:	SNYSIGYSNS TSWGSYSVSA QRSWNEDGDT DDSVYLSFTI PIEKLLGTEQ RTSGFQSIDT 
601:	QISSDFKGNN QLNVSSSGYS DNARVSYSVN TGYTMNKASK DLSYVGGYAS YESPWGTLAG 
661:	SISANSDNSR QVSLSTDGGF VLHSGGLTFS NDSFSDSDTL AVVQAPGAQG ARINYGNSTI 
721:	DRWGYGVTSA LSPYHENRIA LDINDLENDV ELKSTSAVAV PRQGSVVFAD FETVQGQSAI 
781:	MNITRSDGKN IPFAADIYDE QGNVIGNVGQ GGQAFVRGIE QQGNISIKWL EQSKPVSCLA 
841:	HYQQSPEAEK IAQSIILNGI RCQIQ