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1.B.11.3.8
Usher, Caf1A, important for F1 antigen assembly

Accession Number:P26949
Protein Name:F1 capsule-anchoring protein
Length:833
Molecular Weight:93003.00
Species:Yersinia pestis [632]
Location1 / Topology2 / Orientation3: Cell outer membrane1 / Multi-pass membrane protein2
Substrate Fimbrial subunits

Cross database links:

HEGENOM: HBG511492
Entrez Gene ID: 1149093    1149243    1172838    2767657    3077339   
Pfam: PF00577   
KEGG: ype:YPMT1.83    ypm:YP_pMT083   

Gene Ontology

GO:0009279 C:cell outer membrane
GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0005215 F:transporter activity

References (5)

[1] “A new gene of the f1 operon of Y. pestis involved in the capsule biogenesis.”  Karlyshev A.V.et.al.   1551441
[2] “Complete DNA sequence and detailed analysis of the Yersinia pestis KIM5 plasmid encoding murine toxin and capsular antigen.”  Lindler L.E.et.al.   9826348
[3] “Structural organization of virulence-associated plasmids of Yersinia pestis.”  Hu P.et.al.   9748454
[4] “Genome sequence of Yersinia pestis, the causative agent of plague.”  Parkhill J.et.al.   11586360
[5] “Complete genome sequence of Yersinia pestis strain 91001, an isolate avirulent to humans.”  Song Y.et.al.   15368893
Structure:
2XET   3FCG   4B0E   4B0M     

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MRYSKLFLCA GLTLATLPCW GRAYTFDSTM LDTNSGESID VSLFNQGLQL PGNYFVNVFV 
61:	NGRKVDSGNI DFRLEKHNGK ELLWPCLSSL QLTKYGIDID KYPDLIKSGT EQCVDLLAIP 
121:	HSDVQFYFNQ QKLSLIVPPQ ALLPRFDGIM PMQLWDDGIP ALFMNYNTNM QTRKFREGGK 
181:	SLDSYYAQLQ PGLNIGAWRF RSSTSWWKQQ GWQRSYIYAE RGLNTIKSRL TLGETYSDSS 
241:	IFDSIPIKGI KIASDESMVP YYQWNFAPVV RGIARTQARV EVLRDGYTVS NELVPSGPFE 
301:	LANLPLGGGS GELKVIIHES DGTKQVFTVP YDTPAVALRK GYFEYSMMGG EYRPANDLTQ 
361:	TSYVGALGMK YGLPRNLTLY GGLQGSQNYH AAALGIGAML GDFGAISTDV TQADSQKNKQ 
421:	KKESGQRWRV RYNKYLQSGT SLNIASEEYA TEGFNKLADT LNTYCKPNTR NDCRFDYAKP 
481:	KNKVQFNLSQ SIPGSGTLNF SGYRKNYWRD SRSTTSFSVG YNHFFRNGMS LTLNLSKTQN 
541:	INKYGEKTSE LLSNIWLSFP LSRWLGNNSI NSNYQMTSDS HGNTTHEVGV YGEAFDRQLY 
601:	WDVRERFNEK GRKYTSNALN LNYRGTYGEI SGNYSYDQTQ SQLGIGVNGN MVITQYGITA 
661:	GQKTGDTIAL VQAPDISGAS VGYWPGMKTD FRGYTNYGYL TPYRENKVEI NPVTLPNDAE 
721:	ITNNIVSVIP TKGAVVLAKF NARIGGRLFL HLKRSDNKPV PFGSIVTIEG QSSSSGIVGD 
781:	NSGVYLTGLP KKSKILVKWG RDKNQSCSSN VVLPEKTDIS GAYRLSTTCI LNN