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1.B.12.3.2
Autoexporter of adhesion and penetration protein

Accession Number:P45387
Protein Name:Hap
Length:1394
Molecular Weight:155441.00
Species:Haemophilus influenzae [727]
Number of TMSs:1
Location1 / Topology2 / Orientation3: Cell outer membrane1 / Multi-pass membrane protein2
Substrate Adhesins

Cross database links:

Pfam: PF02395    PF03212   

Gene Ontology

GO:0009279 C:cell outer membrane
GO:0009986 C:cell surface
GO:0005576 C:extracellular region
GO:0016021 C:integral to membrane
GO:0042597 C:periplasmic space
GO:0005886 C:plasma membrane
GO:0005515 F:protein binding
GO:0004252 F:serine-type endopeptidase activity
GO:0007155 P:cell adhesion
GO:0006508 P:proteolysis

References (1)

[1] “A Haemophilus influenzae IgA protease-like protein promotes intimate interaction with human epithelial cells.”  St Geme J.W. IIIet.al.   7830568
Structure:
3SYJ     

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
Window Size: Angle:  
FASTA formatted sequence
1:	MKKTVFRLNF LTACISLGIV SQAWAGHTYF GIDYQYYRDF AENKGKFTVG AQNIKVYNKQ 
61:	GQLVGTSMTK APMIDFSVVS RNGVAALVEN QYIVSVAHNV GYTDVDFGAE GNNPDQHRFT 
121:	YKIVKRNNYK KDNLHPYEDD YHNPRLHKFV TEAAPIDMTS NMNGSTYSDR TKYPERVRIG 
181:	SGRQFWRNDQ DKGDQVAGAY HYLTAGNTHN QRGAGNGYSY LGGDVRKAGE YGPLPIAGSK 
241:	GDSGSPMFIY DAEKQKWLIN GILREGNPFE GKENGFQLVR KSYFDEIFER DLHTSLYTRA 
301:	GNGVYTISGN DNGQGSITQK SGIPSEIKIT LANMSLPLKE KDKVHNPRYD GPNIYSPRLN 
361:	NGETLYFMDQ KQGSLIFASD INQGAGGLYF EGNFTVSPNS NQTWQGAGIH VSENSTVTWK 
421:	VNGVEHDRLS KIGKGTLHVQ AKGENKGSIS VGDGKVILEQ QADDQGNKQA FSEIGLVSGR 
481:	GTVQLNDDKQ FDTDKFYFGF RGGRLDLNGH SLTFKRIQNT DEGAMIVNHN TTQAANVTIT 
541:	GNESIVLPNG NNINKLDYRK EIAYNGWFGE TDKNKHNGRL NLIYKPTTED RTLLLSGGTN 
601:	LKGDITQTKG KLFFSGRPTP HAYNHLNKRW SEMEGIPQGE IVWDHDWINR TFKAENFQIK 
661:	GGSAVVSRNV SSIEGNWTVS NNANATFGVV PNQQNTICTR SDWTGLTTCQ KVDLTDTKVI 
721:	NSIPKTQING SINLTDNATA NVKGLAKLNG NVTLTNHSQF TLSNNATQIG NIRLSDNSTA 
781:	TVDNANLNGN VHLTDSAQFS LKNSHFSHQI QGDKGTTVTL ENATWTMPSD TTLQNLTLNN 
841:	STITLNSAYS ASSNNTPRRR SLETETTPTS AEHRFNTLTV NGKLSGQGTF QFTSSLFGYK 
901:	SDKLKLSNDA EGDYILSVRN TGKEPETLEQ LTLVESKDNQ PLSDKLKFTL ENDHVDAGAL 
961:	RYKLVKNDGE FRLHNPIKEQ ELHNDLVRAE QAERTLEAKQ VEPTAKTQTG EPKVRSRRAA 
1021:	RAAFPDTLPD QSLLNALEAK QAELTAETQK SKAKTKKVRS KRAVFSDPLL DQSLFALEAA 
1081:	LEVIDAPQQS EKDRLAQEEA EKQRKQKDLI SRYSNSALSE LSATVNSMLS VQDELDRLFV 
1141:	DQAQSAVWTN IAQDKRRYDS DAFRAYQQQK TNLRQIGVQK ALANGRIGAV FSHSRSDNTF 
1201:	DEQVKNHATL TMMSGFAQYQ WGDLQFGVNV GTGISASKMA EEQSRKIHRK AINYGVNASY 
1261:	QFRLGQLGIQ PYFGVNRYFI ERENYQSEEV RVKTPSLAFN RYNAGIRVDY TFTPTDNISV 
1321:	KPYFFVNYVD VSNANVQTTV NLTVLQQPFG RYWQKEVGLK AEILHFQISA FISKSQGSQL 
1381:	GKQQNVGVKL GYRW