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1.B.12.4.7
Vacuolating Autotransporter-1, Vat (1376 aas; protease; pertactin-like passenger domain; virulence factor)

Accession Number:A1A7W8
Protein Name:Vacuolating autotransporter
Length:1376
Molecular Weight:148018.00
Species:Escherichia coli O1:K1 / APEC [405955]
Number of TMSs:1
Substrate Protease, Vat

Cross database links:

eggNOG: COG3468
HEGENOM: HBG467630
Entrez Gene ID: 4492735   
Pfam: PF03797    PF02395   
KEGG: ecv:APECO1_1712   

Gene Ontology

GO:0019867 C:outer membrane
GO:0004252 F:serine-type endopeptidase activity
GO:0006508 P:proteolysis

References (1)

[1] “The genome sequence of avian pathogenic Escherichia coli strain O1:K1:H7 shares strong similarities with human extraintestinal pathogenic E. coli genomes.”  Johnson T.J.et.al.   17293413

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
Window Size: Angle:  
FASTA formatted sequence
1:	MNKIYALKYC YITNTVKVVS ELARRVCKGS TRRGKRLSVL TSLALSALLP TVAGASTVGG 
61:	NNPYQTYRDF AENKGQFQAG ATNIPIFNNK GELVGHLDKA PMVDFSSVNV SSNPGVATLI 
121:	NPQYIASVKH NKGYQSVSFG DGQNSYHIVD RNEHSSSDLH TPRLDKLVTE VAPATVTSSS 
181:	TADILNPSKY SAFYRAGSGS QYIQDSQGKR HWVTGGYGYL TGGILPTSFF YHGSDGIQLY 
241:	MGGNIHDHSI LPSFGEAGDS GSPLFGWNTA KGQWELVGVY SGVGGGTNLI YSLIPQSFLS 
301:	QIYSEDNDAP VFFNASSGAP LQWKFDSSTG TGSLKQGSDE YAMHGQKGSD LNAGKNLTFL 
361:	GHNGQIDLEN SVTQGAGSLT FTDDYTVTTS NGSTWTGAGI IVDKDASVNW QVNGVKGDNL 
421:	HKIGEGTLVV QGTGVNEGGL KVGDGTVVLN QQADSSGHVQ AFSSVNIASG RPTVVLADNQ 
481:	QVNPDNISWG YRGGVLDVNG NDLTFHKLNA ADYGATLGNS SDKTANITLD YQTRPANVKV 
541:	NEWSSSNRGT VGSLYIYNNP YTHTVDYFIL KTSSYGWFPT GQVSNEHWEY VGHDQNSAQA 
601:	LLANRINNKG YLYHGKLLGN INFSNKATPG TTGALVMDGS ANMSGTFTQE NGRLTIQGHP 
661:	VIHASTSQSI ANTVSSLGDN SVLTQPTSFT QDDWENRTFS FGSLVLKDTD FGLGRNATLN 
721:	TTIQADNSSV TLGDSRVFID KKDGQGTAFT LEEGTSVATK DADKSVFNGT VNLDNQSVLN 
781:	INEIFNGGIQ ANNSTVNISS DSAVLENSTL TSTALNLNKG ANVLASQSFV SDGPVNISDA 
841:	TLSLNSRPDE VSHTLLPVYD YAGSWNLKGD DARLNVGPYS MLSGNINVQD KGTVTLGGEG 
901:	ELSPDLTLQN QMLYSLFNGY RNTWSGSLNA PDATVSMTDT QWSMNGNSTA GNMKLNRTIV 
961:	GFNGGTSSFT TLTTDNLDAV QSAFVMRTDL NKADKLVINK SATGHDNSIW VNFLKKPSDK 
1021:	DTLDIPLVSA PEATADNLFR ASTRVVGFSD VTPTLSVRKE DGKKEWVLDG YQVARNDGQG 
1081:	KAAATFMHIS YNNFITEVNN LNKRMGDLRD INGEAGTWVR LLNGSGSADG GFTDHYTLLQ 
1141:	MGADRKHELG SMDLFTGVMA TYTDTDASAG LYSGKTKSWG GGFYASGLFR SGAYFDLIAK 
1201:	YIHNENKYDL NFAGAGKQNF RSHSLYAGAE VGYRYHLTDT TFVEPQAELV WGRLQGQTFN 
1261:	WNDSGMDVSM RRNSVNPLVG RTGVVSGKTF SGKDWSLTAR AGLHYEFDLT DSADVHLKDA 
1321:	AGEHQINGRK DGRMLYGVGL NARFGDNTRL GLEVERSAFG KYNTDDAINA NIRYSF