TCDB is operated by the Saier Lab Bioinformatics Group
« See all members of the family


1.B.12.5.5
Autotransporter-1, BigA (1953 aas) (Lauri et al. 2011).

Accession Number:P25927
Protein Name:Putative surface-exposed virulence protein BigA
Length:1953
Molecular Weight:200151.00
Species:Salmonella typhimurium [90371]
Number of TMSs:1
Substrate Protein virulence factor

Cross database links:

HEGENOM: HBG468172 HBG468172 HBG468172
Entrez Gene ID: 1255001   
KEGG: stm:STM3478   

Gene Ontology

GO:0009405 P:pathogenesis

References (2)

[1] “Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.”  McClelland M.et.al.   11677609
[2] “High-level expression of Escherichia coli NADPH-sulfite reductase: requirement for a cloned cysG plasmid to overcome limiting siroheme cofactor.”  Wu J.Y.et.al.   1987123

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
Window Size: Angle:  
FASTA formatted sequence
1:	MNPMQKKKLI SIAIALTLQS YYIPAIAAEN NDDEKECPSN ISSLPKEKRA KLSPTCLATP 
61:	ENDNHWGWVA GGVAALVAGV AIGVENNGGG DSNHSYTPPK PDNGGDVTPP DDGGNVTPPD 
121:	DGGNVTPPDD GGDDNVTPPD DSGDDDVAPP DDSGDDDVTP PDDSGDDDVT PPDDSGDGDV 
181:	TPPDDSGDDD VTPPDDSGDD DVTPPDDSGD DDVTPPDDSG DDDVTPPDDS GDDDVTPPDD 
241:	SGDDDDTPPD DSVITFSNGV TIDKGKDTLT FDSFKLDNGS VLEGAVWNYS EQDNQWQLTT 
301:	ADGKTLNVTG WDVTDANAAV IEGTQENGLY WKYDSRGYLI IADDNTTVIS GDDQAHNSDR 
361:	GMDISGQDRT GVIISGDRTV NTLTGDSSVT DGATGMVISG DGTTNTISGH STVDNATGAL 
421:	ISGNGTTTNF AGDIAVSGGG TAIIIDGDNA TIKNTGTSDI SGAGSTGTVI DGNNARVNND 
481:	GDMTITDGGT GGHITGDNVV IDNAGSTTVS GADATALYIE GDNALVINEG NQTISGGAVG 
541:	TRIDGDDAHT TNTGDIAVDG AGSAAVIING DNGSLTQAGD LLVTDGAMGI ITYGTGNEAK 
601:	NTGNATVRDA DSVGFVVAGE KNTFKNKGDI DVSLNGTGAL VSGDMSQVTL DGDINVVSVQ 
661:	DSEGVFSSAT GVSVSGDSNA VDITGNVNIS ADYGQDDLAA GAPPLTGVVV GGNGNTVTLN 
721:	GALNIDDNDL SATGGQYLDV VGLSVTGDDN DVEIDGGINI THSEDPLDGT SADITGISVS 
781:	GNSTVTLNGH STIDTNTVVG GHVVLARVNN GGSLILGDDS VVDVNVSYIP TGYYTYNALL 
841:	MADGEGTSIE NKGDITSHGV YSVIRADNGS EVSNSGDILV YATSSNSSED RAAITRASGE 
901:	GSAVHNKAGG DITLISDQTP QGSGGIEVYP LKWYTHTFYA MMASDYGDVV NDEGATIHLQ 
961:	GAGVYGVTAS RGKALNEGNI YLDGLVPTLD DENNITSTSY WQPSSLYLTS SGMVAGSTDA 
1021:	DGDATAINTG NITVNNAGFG MMALNGGTAI NQGVITLTAD DGVTGQADEL VGMAALNGGV 
1081:	VINDTSGVIN IDADYGQAFL SDSSSYIINN GSINLNGSPM DDTDSHMGGT PTDKIWIQSL 
1141:	PGSGDSDTRT SDTGFFTAGT LANYGTETLN GDVDVNGGWL YNEAGASLTV NGTVTINGGA 
1201:	NALANYGTLD ADAISTWHSL FNEADGSITT DLLTLNGDVT FYNNGDFTGS IAGTSYQQEI 
1261:	VNTGDMTVAE DGKSLVSGSF YFYNEEDATL TNSGSAVEGG ENTIINLTRA NDSLTQVNSG 
1321:	TITATNGYSA ITTVNGSNDP KWIWNTATGV INGINPDAPL INLGRGYNFG NQGTINVQGD 
1381:	NAVAISGGTS SYVINLVNSG TINVGTEQGK EDGTNGTGLI GIKGNGNATT INNTADGVIN 
1441:	VYADDSYAFG GKTKAIINNG EINLLCDSGC DIYAPGTTGT QNDHNGTADI VIPDATTAPT 
1501:	EGSIPTPPAD PNAPQQLSNY IVGTNADGSS GTLKANNLVI GDNVKVDTGF TSGTADTTVV 
1561:	VDNAFTGSNI QGADNITSTS VVWNAQGSQD ADGNVDVTMT KNAYADVATD SSVSDVAQAL 
1621:	DAGYTNNELY TSLNVGTTAE LNSALKQVSG AQATTVFREA RVLSNRFTML ADAAPQIKDG 
1681:	LAFNVVAKGD PRAELGNDTQ YDMLALRQTL DLTASQNLTL EYGIARLDGD GSKTAGDNGL 
1741:	TGGYSQFFGL KHSMAFDEGL AWNNSLRYDV HNLDSSRSVA YGDVNKIADS DMRQQYLEFR 
1801:	SEGAKTFTMM GDALKVTPYA GVKFRHTMED GYKERSAGDF NLSMNSGNET AVDSIVGLKL 
1861:	DYAGKDGWSA TATLEGGPNL SYSKSQRTAS LQGAAGQSFG VDDGQKGGGV NGLATIGVKY 
1921:	SSNDTALHLD AYQWKEDGIS DKGFMLNVKK TFR