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1.B.12.9.2
The serine protease autotransporter, SphB1

Accession Number:Q7W0C9
Protein Name:Autotransporter subtilisin-like protease
Length:932
Molecular Weight:99648.00
Species:Bordetella pertussis [520]
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate Serine proteases

Cross database links:

HEGENOM: HBG354774
RefSeq: NP_879104.1   
Entrez Gene ID: 2664729   
Pfam: PF03797    PF00082   
BioCyc: BPER257313:BP0216-MONOMER   
KEGG: bpe:BP0216   

Gene Ontology

GO:0019867 C:outer membrane
GO:0004252 F:serine-type endopeptidase activity
GO:0006508 P:proteolysis

References (1)

[1] “Comparative analysis of the genome sequences of Bordetella pertussis, Bordetella parapertussis and Bordetella bronchiseptica.”  Parkhill J.et.al.   12910271

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MMPPPAVPPQ LPEVPAADLP RVRAPLSTYR RPQRTDFVTP TGGPFFAKQD KALNTIDLKM 
61:	AHDLKLRGYR VKVAVVDEGV RSDHPLLNVE KKYGGDYMAD GTRTYPDPKR QGRHGTSVAL 
121:	VLAGQDTDTY RGGVAPNADL YSANIGTRAG HVSDEAAFHA WNDLLGHGIK IFNNSFATEG 
181:	PEGEQRVKED RNEYHSAANK QNTYIGRLDR LVRDGALLIF AAGNGRPSGR AYSEVGSVGR 
241:	TPRVEPHLQR GLIVVTAVDE NGRLETWANR CGQAQQWCLA APSTAYLPGL DKDNPDSIHV 
301:	EQGTSLSAPL VTGAAVLVQD RFRWMDNDNL RTTLLTTAQD KGPYGVDPQY GWGVLDVGRA 
361:	VQGPAQFAFG DFVARVTDTS TFGNDISGAG GLVVDGPGAL VLAGSNTYAG RTTIKRGTLD 
421:	VFGSVTSAVT VEPGGTLTGI GTVGTVTNQG TVVNKEAGLH VKGDYSQTAQ GLLVTDIGSL 
481:	LDVSGRASLA GRLHVDDIRP GYVGGDGKSV PVIKAGAVSG VFATLTRSPG LLLNARLDYR 
541:	PQAVYLTMRR AERVHAAAQR GADDGRRASV LAVAERLDAA MRELDALPES QRDAAAPAAA 
601:	IGRIQRVQSR KVLQDNLYSL AGATYANAAA VNTLEQNRWM DRLENHLAQA GGERVAAIAE 
661:	YRHGQLRWRP DGLQGRQRGN GIMLGLAREV SAGLSLAAAL THSRTHWDES SGAPARDNAA 
721:	MTTPGVLLGA RRAWEDGWFV QGALGYSRYR NQATRHISLG DAGHTVGATA RGHVWQADAG 
781:	LGRQWTLAPG HTLAPRAGLQ LTHLRQQGFS ESGAQGLGLR AHALTRTVPT LWAQLQSRHA 
841:	FMLGATPMTA QLQLGVWHDL RARRYAASGG FAGLAQDQGA SGYWPVPRTR VQGALGLRAE 
901:	FAPGLVLGLG YTGQLATHWV DHQLSASLTY RY