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1.B.14.1.6
Ferripyoverdine/pyocin S3 receptor, FpvA (Adams et al., 2006; Nader et al., 2007; Schalk et al., 2009Nader et al., 2011)

Accession Number:P48632
Protein Name:FpvA aka PA2398
Length:815
Molecular Weight:91167.00
Species:Pseudomonas aeruginosa [287]
Number of TMSs:1
Location1 / Topology2 / Orientation3: Cell outer membrane1
Substrate Ferripyoverdine, Pyocin S3

Cross database links:

HEGENOM: HBG576339
RefSeq: NP_251088.1   
Entrez Gene ID: 878605   
Pfam: PF07715    PF07660    PF00593   
Drugbank: Drugbank Link   
BioCyc: PAER208964:PA2398-MONOMER   
KEGG: pae:PA2398   

Gene Ontology

GO:0009279 C:cell outer membrane
GO:0005886 C:plasma membrane
GO:0005506 F:iron ion binding
GO:0004872 F:receptor activity
GO:0015343 F:siderophore-iron transmembrane transporter ...
GO:0006826 P:iron ion transport
GO:0015891 P:siderophore transport

References (3)

[1] “Cloning and nucleotide sequence analysis of the ferripyoverdine receptor gene fpvA of Pseudomonas aeruginosa.”  Poole K.et.al.   8335619
[2] “Characterisation of the pvdE gene which is required for pyoverdine synthesis in Pseudomonas aeruginosa.”  McMorran B.J.et.al.   8918232
[3] “Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic pathogen.”  Stover C.K.et.al.   10984043
Structure:
1XKH   2IAH   2O5P   2W16   2W6T   2W6U   2W75   2W76   2W77   2W78   [...more]

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MPAPHGLSPL SKAFLMRRAF QRRILPHSLA MALSLPLAGY VQAQEVEFDI PPQALGSALQ 
61:	EFGRQADIQV LYRPEEVRNK RSSAIKGKLE PNQAITELLR GTGASVDFQG NAITISVAEA 
121:	ADSSVDLGAT MITSNQLGTI TEDSGSYTPG TIATATRLVL TPRETPQSIT VVTRQNMDDF 
181:	GLNNIDDVMR HTPGITVSAY DTDRNNYYAR GFSINNFQYD GIPSTARNVG YSAGNTLSDM 
241:	AIYDRVEVLK GATGLLTGAG SLGATINLIR KKPTHEFKGH VELGAGSWDN YRSELDVSGP 
301:	LTESGNVRGR AVAAYQDKHS FMDHYERKTS VYYGILEFDL NPDTMLTVGA DYQDNDPKGS 
361:	GWSGSFPLFD SQGNRNDVSR SFNNGAKWSS WEQYTRTVFA NLEHNFANGW VGKVQLDHKI 
421:	NGYHAPLGAI MGDWPAPDNS AKIVAQKYTG ETKSNSLDIY LTGPFQFLGR EHELVVGTSA 
481:	SFSHWEGKSY WNLRNYDNTT DDFINWDGDI GKPDWGTPSQ YIDDKTRQLG SYMTARFNVT 
541:	DDLNLFLGGR VVDYRVTGLN PTIRESGRFI PYVGAVYDLN DTYSVYASYT DIFMPQDSWY 
601:	RDSSNKLLEP DEGQNYEIGI KGEYLDGRLN TSLAYFEIHE ENRAEEDALY NSKPTNPAIT 
661:	YAYKGIKAKT KGYEAEISGE LAPGWQVQAG YTHKIIRDDS GKKVSTWEPQ DQLSLYTSYK 
721:	FKGALDKLTV GGGARWQGKS WQMVYNNPRS RWEKFSQEDY WLVDLMARYQ ITDKLSASVN 
781:	VNNVFDKTYY TNIGFYTSAS YGDPRNLMFS TRWDF