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1.B.14.1.8
The Ferripyochelin receptor, FptA (Michel et al., 2007). In addition to Fe3+, FptA takes up Co2+, Ga3+, and Ni2+ at low rates (Braud et al., 2009).

Accession Number:P42512
Protein Name:Fe(3+)-pyochelin receptor
Length:720
Molecular Weight:79992.00
Species:Pseudomonas aeruginosa [287]
Number of TMSs:1
Location1 / Topology2 / Orientation3: Cell outer membrane1
Substrate Ferripyochelin, Ni2+

Cross database links:

HEGENOM: HBG576339
RefSeq: NP_252911.1   
Entrez Gene ID: 880419   
Pfam: PF07715    PF00593   
Drugbank: Drugbank Link   
BioCyc: PAER208964:PA4221-MONOMER   
KEGG: pae:PA4221   

Gene Ontology

GO:0009279 C:cell outer membrane
GO:0005886 C:plasma membrane
GO:0005506 F:iron ion binding
GO:0004872 F:receptor activity
GO:0015343 F:siderophore-iron transmembrane transporter ...
GO:0006826 P:iron ion transport
GO:0015891 P:siderophore transport

References (2)

[1] “FptA, the Fe(III)-pyochelin receptor of Pseudomonas aeruginosa: a phenolate siderophore receptor homologous to hydroxamate siderophore receptors.”  Ankenbauer R.G.et.al.   8288523
[2] “Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic pathogen.”  Stover C.K.et.al.   10984043
Structure:
1XKW     

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MKTETKVIKG RQGIARNRHT PLCLGLLLAL SPLAAAVADA RKDGETELPD MVISGESTSA 
61:	TQPPGVTTLG KVPLKPRELP QSASVIDHER LEQQNLFSLD EAMQQATGVT VQPFQLLTTA 
121:	YYVRGFKVDS FELDGVPALL GNTASSPQDM AIYERVEILR GSNGLLHGTG NPAATVNLVR 
181:	KRPQREFAAS TTLSAGRWDR YRAEVDVGGP LSASGNVRGR AVAAYEDRDY FYDVADQGTR 
241:	LLYGVTEFDL SPDTLLTVGA QYQHIDSITN MAGVPMAKDG SNLGLSRDTY LDVDWDRFKW 
301:	DTYRAFGSLE QQLGGGWKGK VSAEYQEADS RLRYAGSFGA IDPQTGDGGQ LMGAAYKFKS 
361:	IQRSLDANLN GPVRLFGLTH ELLGGVTYAQ GETRQDTARF LNLPNTPVNV YRWDPHGVPR 
421:	PQIGQYTSPG TTTTTQKGLY ALGRIKLAEP LTLVVGGRES WWDQDTPATR FKPGRQFTPY 
481:	GGLIWDFARD WSWYVSYAEV YQPQADRQTW NSEPLSPVEG KTYETGIKGE LADGRLNLSL 
541:	AAFRIDLENN PQEDPDHPGP PNNPFYISGG KVRSQGFELE GTGYLTPYWS LSAGYTYTST 
601:	EYLKDSQNDS GTRYSTFTPR HLLRLWSNYD LPWQDRRWSV GGGLQAQSDY SVDYRGVSMR 
661:	QGGYALVNMR LGYKIDEHWT AAVNVNNLFD RTYYQSLSNP NWNNRYGEPR SFNVSLRGAF