TCDB is operated by the Saier Lab Bioinformatics Group
« See all members of the family


1.B.14.2.10
Heme transporter BhuA (Brucella heme uptake protein A)

Accession Number:Q2YJB2
Protein Name:Heme transporter BhuA
Length:661
Molecular Weight:72931.00
Species:Brucella abortus (strain 2308) [359391]
Location1 / Topology2 / Orientation3: Cell outer membrane1
Substrate Heme

Cross database links:

eggNOG: COG1629
HEGENOM: HOG000143472
Entrez Gene ID: 3828017   
Pfam: PF07715    PF00593   
KEGG: bmf:BAB2_1150   

Gene Ontology

GO:0009279 C:cell outer membrane
GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0004872 F:receptor activity
GO:0005215 F:transporter activity

References (2)

[1] “Whole-genome analyses of speciation events in pathogenic Brucellae.”  Chain P.S.et.al.   16299333
[2] “Brucella abortus requires the heme transporter BhuA for maintenance of chronic infection in BALB/c mice.”  Paulley J.T.et.al.   17709407

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
Window Size: Angle:  
FASTA formatted sequence
1:	MKFTRTLVLV STSLLATVAT SQAQEVKRDT KKQGEVVLKP ITIISHGKDN IEATGGTVLT 
61:	YKDIEKLQPA NVSELFSRQS SIAVSGGGGP SKRIHVLGME QSNLAVSVDG VPQTATSWHH 
121:	TGSNVIDPAF LKRVEVEAGA AAADSGFGAA AGAIRYETVN ALDLLEPGKT FGARIIGSYG 
181:	TNGRGFSGST AAYGLKDGFD WLLMLHGTSG HNYKNGDGTE ILGTEPAARN ILGKAGYEFD 
241:	GNRIDIGYER SRDKADRLIK MNMGLPGDTE YPLEVARDSV NIKYTRTDAT DMWDPEVQFY 
301:	YNRNDYWRND YQNRTNGNMI LKEDLYGGKL QNTFTIDYGK ITAGIDFGKH DYNTDNYGHN 
361:	DRRYRKFNTQ QVGAFTQGRF EFDNGFSLST GARYDYSRFA DWNDEVFSDS GASVNGTLSY 
421:	KFNEHIEVFA GASRTWLGYV LGDYGYVHAR NNAFYTDPTF SPGRARNYKA GVNFGGADWS 
481:	AGITLFDTRI AGLPNYDSQK LGNDPEEYRS RGFTLNARYI WNYTTIGATF TKAKVTAGDD 
541:	PVLPNSGSFM PIGDMATLFI DQEIPDYNMK VGATLAWAGR ISDEAATAAN FYDQPAYTVV 
601:	NAYAEWNPPA VKNMTLRVGV ENLFNENYYE RTSFAPSQNR GGIDAVWAPG RTFTFQTAFK 
661:	F