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1.B.14.2.8
The heme-iron (from hemin and hemoglobin) utilization receptor, BhuR (Brickman et al., 2006; Vanderpool and Armstrong, 2004).

Accession Number:Q7VSQ4
Protein Name:Outer membrane heme receptor
Length:845
Molecular Weight:91713.00
Species:bordetella pertussis [520]
Location1 / Topology2 / Orientation3: Cell outer membrane1
Substrate Hemin, Hemoglobin

Cross database links:

HEGENOM: HBG299377
RefSeq: NP_879220.1   
Entrez Gene ID: 2664030   
Pfam: PF07715    PF07660    PF00593   
BioCyc: BPER257313:BP0347-MONOMER   
KEGG: bpe:BP0347   

Gene Ontology

GO:0009279 C:cell outer membrane
GO:0005886 C:plasma membrane
GO:0004872 F:receptor activity
GO:0005215 F:transporter activity
GO:0006810 P:transport

References (1)

[1] “Comparative analysis of the genome sequences of Bordetella pertussis, Bordetella parapertussis and Bordetella bronchiseptica.”  Parkhill J.et.al.   12910271

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MRGALAACAL AGTLAAAPAA AQPTAAPASA GARAWHIDAG PLGEALARFA DQAGITLLYD 
61:	PAAVRGRASA GLQGVYSVPD GLARLLDGSG LDARQRGAGT YVLQALPAGP VAQLAPVTIE 
121:	ADGVRADPAW ARTATRRELD ARQVLDWSDI GKRVDPGVNY NRRTKSINIR GLDENRVVTR 
181:	IDGIRLPWLD DGARGIQGGL NAVDFNTLSR LDVVRGADSS AAGSGALGGL ADLRTLEPAD 
241:	LLRDGRRFGA LAKSDYDSAD ASWGLNAALA GQVHDDTSWL LQAGTRNGHD LDNRADTGGY 
301:	GSKRSQPSPE DYAQNNFLLK LQQRIDGGHR LGLTGEYFKR RADLDQMYQQ GAGTSYQYGA 
361:	NRTHEETTRK RVSLDYQYNA PQAGAAIDSA RAMVYWQRLR LDSSQDARRT RDGRAYARPG 
421:	DPYFYGYPSG PYGRSNSIQE SILGVNGELS SRFEGMVSQR VTIGGEWYGN RTEQYSDGYD 
481:	NCPAIPPGTP APMGPRLCDM LHTNQADMPR VKGSQWAIWA QDEIAFADGR YILTPSLRYD 
541:	HYEQKPQQGG GYQNNPNAGA LPPSSSGGRF SPKLLGTWKA REALTLYAQY GFGYRAPSAT 
601:	ELYTNYGGPG TYLRVGNPSL KPETSKGWEL GARLGDDQLG GAVSLFDNRY QNFIDKNVPL 
661:	GKGSPQWQPA WDGQYPLGVT GLANRARVRI YGAEASAHWR FAPNWRTWGS LAWAVGKDEN 
721:	TGQHLNSVPP LKAILGLGYQ RDEWGIDAML TAATRRDDVQ YPEASASARY ADFQAPGYGV 
781:	VDLSAYWRPA AVKGLQLQAG VFNLFDKKYW EAINVPTAGA IAIPRPLDWY NEPGRSVRVS 
841:	LTYQY