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1.B.17.2.1
CnrC outer membrane exporter of Ni2+ and Co2+.  Functions with TC# 2.A.6.1.1 and 8.A.1.2.1.

Accession Number:P37974
Protein Name:CnrC
Length:418
Molecular Weight:43760.00
Species:Alcaligenes eutrophus (Ralstonia eutropha) [266264]
Location1 / Topology2 / Orientation3: Cell outer membrane1
Substrate Ni2+, Co2+

Cross database links:

eggNOG: COG1538
HEGENOM: HBG691656
RefSeq: YP_161707.1    YP_582017.1   
Entrez Gene ID: 3187286    4036646   
Pfam: PF02321   
KEGG: rme:Rmet_6208   

Gene Ontology

GO:0005215 F:transporter activity
GO:0006810 P:transport

References (2)

[1] “Characterization of the inducible nickel and cobalt resistance determinant cnr from pMOL28 of Alcaligenes eutrophus CH34.”  Liesegang H.et.al.   8380802
[2] “Regulation of the cnr cobalt and nickel resistance determinant from Ralstonia sp. strain CH34.”  Grass G.et.al.   10671463

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
Window Size: Angle:  
FASTA formatted sequence
1:	MKQVISSFLC RPRFVGSAIW LLPVALSHAA EAPPFPNLLQ QSLALAPAMV AQAANVRAAG 
61:	ADAAQAQAWL NPRIDTVLEN LGAPSSDGLS QRQNTYSITQ PFELGGKRGA RIEVGERNFA 
121:	AAQARERQAQ VAYAAELAVA YATAEAALGR KILATENLAR ANEELAAARA LVDSGKEASL 
181:	RSAQAKASVA AAQAAEAAAT NDATQALARL SAMSGASEPY TAVTSSLLTT QAVVPNAPAA 
241:	LAESPSVRAA EAERNALDAQ VDVERKRWIP DVGVSAGVRR YGWTNSSGYV VGVTASIPLF 
301:	DQNRNGINAA VERVAAAQAR LDSVRLEANV ARQSAISQVA TADKQLAAAS EGEQAAAEAY 
361:	RMGRIGYESG KTPLMELLAV RRALVDARQL TIDARLARVR ALAALAQADG RLAFEESR