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1.B.19.1.1
Cation-selective, glucose-inducible glucose-transporting porin (also transports glycerol, mannitol, fructose, maltose, pentoses, etc.) (Adewoye and Worobec 1999).

Accession Number:Q51485
Protein Name:PORB aka OprB aka PA3186
Length:454
Molecular Weight:50754.00
Species:Pseudomonas aeruginosa [287]
Number of TMSs:1
Location1 / Topology2 / Orientation3: Cell outer membrane1 / Multi-pass membrane protein2
Substrate cations, glucose, glycerol, mannitol, fructose, Maltose, Pentoses

Cross database links:

HEGENOM: HBG640334
RefSeq: NP_251876.1   
Entrez Gene ID: 882788   
Pfam: PF04966   
BioCyc: PAER208964:PA3186-MONOMER   
KEGG: pae:PA3186   

Gene Ontology

GO:0009279 C:cell outer membrane
GO:0005886 C:plasma membrane
GO:0046930 C:pore complex
GO:0005215 F:transporter activity
GO:0008643 P:carbohydrate transport
GO:0006811 P:ion transport

References (5)

[1] “Cloning and nucleotide sequence of the Pseudomonas aeruginosa glucose-selective OprB porin gene and distribution of OprB within the family Pseudomonadaceae.”  Wylie J.L.et.al.   8125108
[2] “Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic pathogen.”  Stover C.K.et.al.   10984043
[3] “Specificity of the glucose channel formed by protein D1 of Pseudomonas aeruginosa.”  Trias J.et.al.   2450582
[4] “Biophysical characterization of OprB, a glucose-inducible porin of Pseudomonas aeruginosa.”  Wylie J.L.et.al.   8132494
[5] “The OprB porin plays a central role in carbohydrate uptake in Pseudomonas aeruginosa.”  Wylie J.L.et.al.   7768797

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MYKNKKTRPA ARTVGCLFAL GALGLGSAAH AAEAFSPNSK WMLGDWGGKR TELLEKGYDF 
61:	KLEYVGEAAA NLDGGYDDDK TGRYTDQFAL GVHMDLEKIL GWKATEFQFT VTERNGKNLS 
121:	NDRIGDPRAG HISSVQEVWG RGQTWRLTQL WLKQQYFDGA LDVKFGRFGE GEDFNSFPCD 
181:	FQNLAFCGSQ VGNWAGSIWY NWPVSQWALR VKYNFAPDWY VQVGAYEQNP SNLETGNGFK 
241:	MSGSGTKGAL LPVELIWQPK VGAEQLPGEY RLGYYYSTAK ADDVYDDVDG QPQGLTGNDF 
301:	KSRGSKHGWW VVAQQQVTSH NGDASRGLSL FANLTVHDKA TNVVDNYQQL GVVYKGPFDA 
361:	RPKDDIGLGI ARIHVNDDVK KRQRLVNQVN GIDDYDNPLY QPLQDTEYNA ELYYGVHVTD 
421:	WLTVRPNLQY IKQPGGVDEV DNALVAGIKI QTVF