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1.B.20.1.2
Outer membrane hemolysin secretion protein, HpmA

Accession Number:P16465
Protein Name:HLYB aka HpmA aka HPMB
Length:561
Molecular Weight:63222.00
Species:Proteus mirabilis [584]
Location1 / Topology2 / Orientation3: Cell outer membrane1
Substrate Hemolysin

Cross database links:

Pfam: PF08479    PF03865   

Gene Ontology

GO:0009279 C:cell outer membrane
GO:0005886 C:plasma membrane
GO:0046930 C:pore complex
GO:0019835 P:cytolysis
GO:0019836 P:hemolysis by symbiont of host erythrocytes
GO:0006811 P:ion transport
GO:0015031 P:protein transport

References (1)

[1] “Nucleotide sequencing of the Proteus mirabilis calcium-independent hemolysin genes (hpmA and hpmB) reveals sequence similarity with the Serratia marcescens hemolysin genes (shlA and shlB).”  Uphoff T.S.et.al.   2407716

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MKKKVVLLTL LSCFSTSGLS ANETGNLGSI SESRRALQDS QREINQLIEQ NRYQQLQEKA 
61:	VNISPTPTLI TESEHCLPIK GVYIQGITLL TEKDLNSLSP LPDQCIKSAD INRLVKELTQ 
121:	RYLQHGYITA RIQFLRPNQH GELGLYAIEG FVERIEGGDR GVNTTLLFPR IKGQPLKLAT 
181:	LDQGLDQANR LQSNKVTVDI LPGTELGGSV IKLSNQRKSP WHLNIASDNY GQKNSGRWLI 
241:	RTNASLDSPL GLSDFVSLNA NITTDNPNTR FNRAYTLLYS IPYGGFTFSS FGSYSEYQFH 
301:	QKLQTRTVNL YGDTTQVGIR GDYAFSRSQK QIDTLNIQVT HKRIRNYFSQ IRLDLSSPKL 
361:	TTIELGINHL QIIPNGVLST NLSVEKAVGW FGAEETPYIA NGNGNDYRFT KVKLFTNWYQ 
421:	RFSLWHSTFL FNSTFLGQYS HDTLPGVEWL SLTDKNAIRG FDQSTLSGDN GGYLRNTLSY 
481:	PYRLNHFSIT PRIGVDIGQV KQHGNYKGWQ GGYGLSSGLN IQYQQAQLDL EVAKGELLYH 
541:	QTNSNKTKDP TQLLVKFSYL F