TCDB is operated by the Saier Lab Bioinformatics Group
« See all members of the family


1.B.20.1.4
The outer membrane haemolysin-like OptA exporter, OptB (OptA, AAG55657, resembles Alveicin B, 1.C.75.1.1) (Choi et al., 2007). Choi and Bernstein (2010) have demonstrated that BpaA is secreted in a two step process, and the C-terminus of OtpA enters the OtpB pore before the N-terminus.

Accession Number:Q8XAN8
Protein Name:Hemolysin activator-related protein
Length:539
Molecular Weight:60957.00
Species:Escherichia coli O157:H7 [83334]
Location1 / Topology2 / Orientation3: Mitochondrion1
Substrate Hemolysin

Cross database links:

HEGENOM: HBG086609
RefSeq: NP_287047.1    NP_309310.1   
Entrez Gene ID: 912949    959178   
Pfam: PF08479    PF03865   
BioCyc: ECOL83334:ECS1283-MONOMER   
KEGG: ece:Z1543    ecs:ECs1283   

References (2)

[1] “Genome sequence of enterohaemorrhagic Escherichia coli O157:H7.”  Perna N.T.et.al.   11206551
[2] “Complete genome sequence of enterohemorrhagic Escherichia coli O157:H7 and genomic comparison with a laboratory strain K-12.”  Hayashi T.et.al.   11258796

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
Window Size: Angle:  
FASTA formatted sequence
1:	MQLRFNFGLL LILCCFQVAA KDSLDNLIKQ QKNADESTLR AHKLEKKDVY SNAQRNAFTL 
61:	GDLPQEKNCF IINRIELEDN FLGGQLISEV QKAIAGRCVG SAGVQKIAAA LQDYYINAGY 
121:	ITTRISIPSQ DISKGKLRFQ VNAGKIEKTI VEGNDISEWM LPFQRNDILN IRDIEQGLEN 
181:	LQRVPDVDVK INIEPGTRDG YSIVHIDTHR GKNWSVRASY NNWGDEETGR YQTTSVGYLF 
241:	NPAKMGDLFY LAGTRSTTGQ YENVSSYYSI PVGYWEYGFF YSKSKSQQVI PLSYISLDYV 
301:	GISEYLSAKA THTVYRDKTK KFAGSAELIR RKSNYTLNGE ELTLQARDMG NIKLGLNYKQ 
361:	QLPGAFWDST LSWQRFLTWF GGEKTPDMQY GDVSPVSNIF NFEGNYTRQI ENGYYNTAFF 
421:	AQYAPRELTL QDKITVGDRW SIRGFENSVG LSGNDGFYIK NTLAFPLPGM KANYYAGLDF 
481:	GQVYQDASYG DESLVGSAVG IDGNIKSLEY NFSVSTPLKY PATLDIDRVN VNFNFSYQM