TCDB is operated by the Saier Lab Bioinformatics Group
TCIDNameDomainKingdom/PhylumProtein(s)
*1.B.35.1.1









The oligogalacturonate-specific porin, KdgM.  The 3-D structure is known at 1.9 Å resolution (Hutter et al. 2014).  KdgM folds into a 12-stranded antiparallel beta-barrel with a circular cross-section defining a transmembrane pore with a minimal radius of 3.1 Å. Most loops that face the cell exterior in vivo are disordered but nevertheless mediate contact between densely packed membrane-like layers in the crystal. The channel is lined by two tracks of arginine residues facing each other across the pore, a feature that is conserved within the KdgM family and is likely to facilitate the diffusion of acidic oligosaccharides (Hutter et al. 2014).

Bacteria
Proteobacteria
KdgM of Erwinia chrysanthemi (Dickeya dadantii)
*1.B.35.1.2









The second oligogalacturonate-specific Gram negative porin, KdgN (60% identical to KdgM; 1.B.35.1.1) (Condemine and Ghazi, 2007).

Bacteria
Proteobacteria
KdgN of Dickeya dadantii (Erwinia carotovora) (Q6D4T8)
*1.B.35.1.3









Alginate-oligosaccharide-specific porin, KdgM (Wargacki et al., 2012).

Bacteria
Proteobacteria
KdgM of Vibrio speldidus (A3UR43)
*1.B.35.1.4









Alginate-oligosaccharide-specific porin, KdgN (Wargacki et al., 2012)

Bacteria
Proteobacteria
KdgN of Vibrio splendidus (A3UR51)
*1.B.35.1.5









KdgM homologue of 227 aas

Bacteria
Proteobacteria
KdgM homologue of Enterobacter cloacae
*1.B.35.1.6









Putative KdgM porin of 224 aas

Bacteria
Proteobacteria
KdgM porin of Serratia marcescens
*1.B.35.1.7









OmpK26 porin (YjhA) of 231 aas; associated with carbapenem resistance (García-Sureda et al. 2011).

Bacteria
Proteobacteria
OmpK26 of Klebsiella pneumoniae
*1.B.35.2.1









The N-acetylneuraminic acid-inducible, anion selective porin, NanC (Condemine et al., 2005). A crystal structure (3.3 Å resolution) is available (2WJQ; Wirth et al., 2009). It forms a 28 Å high 12 stranded β barrel like the autotransporter, NalP. The pore is lined by basic residues (conserved in other KdgM family members) allowing diffusion of acidic oligosaccharides (Wirth et al., 2009).  Single channels of NanC at pH 7.0 have: (1) conductance 100 to 800 pS in 100 mM: KCl to 3 M: KCl), (2) anion over cation selectivity, and (3) two forms of voltage-dependent gating (channel closures above 200 mV). Phosphate interferes with channel conductance (Giri et al. 2012).

Bacteria
Proteobacteria
NanC (YjhA) of E. coli (P69856)
*1.B.35.2.2









OmpL porin. Nearly identical to Salmonella typhimurium YshA which appears to be a 10 β-stranded transmembrane β-barrel which forms a pore with a radius of 0.7nm (Freeman et al., 2011). May be an oligogalacturonate-specific porin (Shevchik and Hugouvieux-Cotte-Pattat, 2003).

Bacteria
Proteobacteria
OmpL of E. coli
*1.B.35.2.3









Putative porin of 233 aas

Bacteria
Bacteroidetes/Chlorobi group
Putative porin of Owenweeksia hongkongensis
*1.B.35.2.4









Uncharacterized protein of 218 aas.  Show extensive sequence similarity with both 1.B.35.2.4 and 9.B.165.1.10.

Bacteria
candidate division Zixibacteria
UP of Zixibacteria bacterium SM1_73
*1.B.35.3.1









Putative porin of 230 aas

Bacteria
Proteobacteria
Putative porin of Vibrio parahaemolyticus
*1.B.35.3.2









Putative porin of 236 aas

Bacteria
Proteobacteria
Putative porin of Psychromonas sp.
*1.B.35.4.1









Putative porin of 263 aas

Bacteria
Proteobacteria
Putative porin of Photobacterium profundum
*1.B.35.4.2









Putative porin of 282 aas

Bacteria
Proteobacteria
Putative porin of Photobacterium profundum
*1.B.35.4.3









Putative porin of 267 aas

Bacteria
Proteobacteria
Porin of Vibrio orientalis