1.B.37 The Leptospira Porin OmpL1 (LP-OmpL1) Family
Spirochetes of the genus Leptospira possess integral outer membrane β-porins, OmpL1, that can form trimeric structures (Shang et al., 1995). OmpL1 has been reconstituted in planar lipid bilayers where an average single channel conductance of 1.1 nS, similar to the major porin activity of native leptospiral membranes, was demonstrated. Haake and Matsunaga (2010) have reviewed the properties of Leptospiral outer membrane proteins.
The reaction catalyzed by OmpL1 is:
small molecules (periplasm) small molecules (out)