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1.B.39.1.3
The anaerobically induced outer membrance porin, OprG. Transports small neutral amino acids (Kucharska et al. 2015). The 3-d structure is available (Touw et al. 2010).  Essential for normal biofilm formation (Ritter et al. 2012). It is an eight-stranded β-barrel monomer that is too narrow to accommodate even the smallest transported amino acid, glycine, raising the question of how OprG facilitates amino acid uptake (Sanganna Gari et al. 2018). Pro-92 of OprG is important for amino acid transport, with a P92A substitution inhibiting transport and the NMR structure of this variant revealing that this substitution produces structural changes in the barrel rim and restricts loop motions. OprG assembles into oligomers in the OM whose subunit interfaces could form a transport channel, and conformational changes in the barrel-loop region may be crucial for its activity (Sanganna Gari et al. 2018).

Accession Number:Q9HWW1
Protein Name:Outer membrane protein OprG
Length:232
Molecular Weight:25194.00
Species:Pseudomonas aeruginosa [287]
Number of TMSs:1
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate Amino acids

Cross database links:

HEGENOM: HBG701154
RefSeq: NP_252756.1   
Entrez Gene ID: 879793   
Pfam: PF03922   
BioCyc: PAER208964:PA4067-MONOMER   
KEGG: pae:PA4067   

Gene Ontology

GO:0009279 C:cell outer membrane

References (1)

[1] “Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic pathogen.”  Stover C.K.et.al.   10984043
Structure:
2X27   2N6L   2N6P     

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FASTA formatted sequence
1:	MRKSWLTASL LALTVASPFA AADIQGHKAG DFIIRGGFAT VDPDDSSSDI KLDGAKQRGT 
61:	KATVDSDTQL GLTFTYMFAD KWGVELVAAT PFNHQVDVKG LGPGLDGKLA DIKQLPPTLL 
121:	LQYYPMGGTN SAFQPYGGLG VNYTTFFDED LASNRKAQGF SSMKLQDSWG LAGELGFDYM 
181:	LNEHALFNMA VWYMDIDTKA SINGPSALGV NKTKVDVDVD PWVYMIGFGY KF