1.C.120 The Pore-forming Toxic Peptide, DinQ (DinQ) Family
DinQ of E. coli is a small transmembrane toxic peptide located in the inner membrane. It's expression is controlled by AgrB antisense RNA and the repressor, LexA (SOS response regulator). Overexpression of dinQ mRNA leads to membrane depolaritzation and loss of cytoplasmic ATP (Weel-Sneve et al. 2013; Brielle et al. 2016). Pore formation is inferred.