TCDB is operated by the Saier Lab Bioinformatics Group
TCIDNameDomainKingdom/PhylumProtein(s)
*1.C.21.1.1









Class I lantibiotic bacteriocin Lacticin 481
Bacteria
Firmicutes
Lacticin 481 of Lactococcus lactis
*1.C.21.1.2









Class I lantibiotic bacteriocin Variacin precursor
Bacteria
Actinobacteria
Variacin of Micrococcus varians
*1.C.21.1.3









Class I lantibiotic bacteriocin Streptococcin A-M29 precursor
Bacteria
Firmicutes
Streptococcin A of Streptococcus pyogenes
*1.C.21.1.4









Class I lantibiotic bacteriocin Salivaricin A precursor
Bacteria
Firmicutes
Salivaricin A precursor of Streptococcus salivarius
*1.C.21.1.5









Nukacin ISK-1 (Okuda et al., 2008)
Bacteria
Firmicutes
Nukacin ISK-1 of Staphylococcus warneri (Q9KWM4)
*1.C.21.1.6









Cyclic bacteriocin, Group II, Butyrivibriocin ARIO (BviA; 80 aas)

Bacteria
Firmicutes
BviA of Butyrivibrio fibrisolvens (Q99Q15)
*1.C.21.1.7









Salivaricin 9 (SivA; 56 aas; 1 or 2 TMSs) (Wescombe et al., 2011)

Bacteria
Firmicutes
SivA of Strepococcus salivarius (Q09I51)
*1.C.21.1.8









Lantibiotic nukacin (Nukacin KQ-1) (Nukacin KQU-131)
Bacteria
Firmicutes
nukA of Staphylococcus hominis
*1.C.21.2.1









Putative lantibiotic bacteriocin precursor of 71 aas (van Heel et al. 2013).

Bacteria
Firmicutes
Bacteriocin of Streptococcus pneumoniae
*1.C.21.2.2









Lichenicidin prepeptide, LanA of 68 aas

Bacteria
Firmicutes
Lichenicidin of Bacillus licheniformis
*1.C.21.2.3









Lantibiotic, mersacidin, of 69 aas

Bacteria
Firmicutes
Mersacidin of Bacillus halodurans
*1.C.21.2.4









Two component Lacticin 3147 (Ltnα of 59 aas and Ltnβ of 65 aas (Draper et al. 2015).  Lacticin 3147 and other lantibiotics target Lipid II to inhibit cell wall synthesis, and then form pores in the membrane (Biswas and Biswas 2014).  They target a large number of bacteria, and several mechanisms of pore-formation have been proposed (Draper et al. 2015).

Bacteria
Firmicutes
Lactincin 3147 of Streptococcus mutans
*1.C.21.2.5









Uncharacterized protein of 55 aas

Bacteria
Firmicutes
UP of Clostridium saccharobutylicum
*1.C.21.2.6









Lantibiotic, mersacadin, MrsA, of 58 aa

Bacteria
Firmicutes
MrsA of Bacillus subtilis