TCDB is operated by the Saier Lab Bioinformatics Group
TCIDNameDomainKingdom/PhylumProtein(s)
*1.C.34.1.1









Tachyplesin I precursor.  It's 3-d pore structure has been examined (Lipkin et al. 2017). Its structure/function and toxicity activities have been reviewed (Edwards et al. 2017).

Eukaryota
Metazoa
Tachyplesin I of Tachypleus tridentatus
*1.C.34.2.1









Polyphemusin I
Eukaryota
Metazoa
Polyphemusin I of Limulus polyphemus
*1.C.34.3.1









Spider peptide, Gomesin, of 84 aas and 1 N-terminal TMS.  Gomesin is active against several Gram-positive bacteria such as Bacillus spp, Staphylococcus spp and E.faecalis, several Gram-negative bacteria such as E. coli, K. pneumoniae,   and Salmonella spp, filamentous fungi such as N. crassa, T. viridae and yeasts such as  C. albicans.  It is active against the parasite L.amazonensis as well. It shows hemolytic activity, permeabilizes cell membranes, and is probably a pore former (Tanner et al. 2018)..

Eukaryota
Metazoa
Gomesin of Acanthoscurria gomesiana (Tarantula spider) (Phormictopus pheopygus)