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1.C.35.4.1
Countin

Accession Number:Q86IV5
Protein Name:Countin-1
Length:258
Molecular Weight:26659.00
Species: [44689]
Number of TMSs:1
Location1 / Topology2 / Orientation3: Secreted1
Substrate small molecules

Cross database links:

HEGENOM: HBG077942
RefSeq: XP_643887.1   
Entrez Gene ID: 8619313   
KEGG: ddi:DDB_0185089   

Gene Ontology

GO:0005576 C:extracellular region
GO:0004871 F:signal transducer activity
GO:0030041 P:actin filament polymerization
GO:0006928 P:cellular component movement
GO:0042593 P:glucose homeostasis
GO:0007275 P:multicellular organismal development
GO:0031158 P:negative regulation of aggregate size invol...
GO:0007162 P:negative regulation of cell adhesion
GO:0030827 P:negative regulation of cGMP biosynthetic pr...
GO:0032114 P:regulation of glucose-6-phosphatase activity
GO:0006110 P:regulation of glycolysis

References (8)

[1] “A cell-counting factor regulating structure size in Dictyostelium.”  Brock D.A.et.al.   10444594
[2] “Sequence and analysis of chromosome 2 of Dictyostelium discoideum.”  Gloeckner G.et.al.   12097910
[3] “The genome of the social amoeba Dictyostelium discoideum.”  Eichinger L.et.al.   15875012
[4] “A precise group size in Dictyostelium is generated by a cell-counting factor modulating cell-cell adhesion.”  Roisin-Bouffay C.et.al.   11090633
[5] “Two cell-counting factors regulate the aggregate size of the cellular slime mold Dictyostelium discoideum.”  Okuwa T.et.al.   11737154
[6] “The different components of a multisubunit cell number-counting factor have both unique and overlapping functions.”  Brock D.A.et.al.   12117815
[7] “CF45-1, a secreted protein which participates in Dictyostelium group size regulation.”  Brock D.A.et.al.   12912898
[8] “A 60-kilodalton protein component of the counting factor complex regulates group size in Dictyostelium discoideum.”  Brock D.A.et.al.   16963635

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MNKLFSLILA LFLVNSAVVS SLDSCSICVD FVGNSLNDLL NIILNSGVIG TCGDLCSAVP 
61:	GGQIVDTVCD LLCDYVGVDE FIKLISDVDP DPIYICEKIS VCKTNDNAAA SLDLVQINPQ 
121:	NGTVGGTFTL SIAYTVTNTI ATGQLAFNII DPTGNAFGDA VLLVQQSPEQ YTQQFQFQAT 
181:	PSEQESFPNG LYTVQALVCE GSCGSPHPNT YTLANGTTTF TISGADSSSM SGAGSFSGSS 
241:	QSTQTGAASG SGSGFALF