TCDB is operated by the Saier Lab Bioinformatics Group
TCIDNameDomainKingdom/PhylumProtein(s)
*1.C.40.1.1









Bacterial permeability inducing protein, BPIP precursor, of 487 aas and 1 N-terminal TMS. 

Eukaryota
Metazoa
BPIP precursor of Homo sapiens
*1.C.40.1.2









LBP (lipopolysaccharide binding protein) precursor
Eukaryota
Metazoa
LBP precursor of Homo sapiens
*1.C.40.1.3









CETP (cholesterylester transfer protein) precursor
Eukaryota
Metazoa
CETP precursor of Oryctolagus cuniculus
*1.C.40.1.4









Phospholipid transfer protein (PLTP) precursor (lipid transfer protein II)
Eukaryota
Metazoa
PLTP of Homo sapiens (493 aas; P55058)
*1.C.40.1.5









NRF5 protein of 551 aas.  Plays a role in the uptake of a range of molecules including phosphatidylserine, lipids and xenobiotic compounds from the intestine to surrounding tissues (Choy and Thomas 1999). Possesses lipid transfer activity and mediates transport of lipids from theintestine to the reproductive tract. Binds phosphatidylserine and plays a role in the efficient clearance of cell corpses by mediating phosphatidylserine appearance on phagocytic cells, thus promoting phagocytic engulfment of apoptotic cells (Zhang et al. 2012). Vital for embryonic development.  Gene deletion leads to extension of the life span (Brejning et al. 2014).

Eukaryota
Metazoa
NRF5 of Caenorhabditis elegans
*1.C.40.1.6









BPI-like protein of 458 aas and 2 TMSs.

Eukaryota
Metazoa
BPI-like protein of Homo sapiens
*1.C.40.1.7









Bactericidal/permeability-increasing protein, BPI of 472 aas and 2 TMSs.
Eukaryota
Metazoa
BPI of Larimichthys crocea (Large yellow croaker) (Pseudosciaena crocea)
*1.C.40.1.8









Cholesteryl ester transfer protein, CETP of 493 aas and 1 TMS.  Involved in the transfer of neutral lipids, including cholesteryl esters and triglycerides, among lipoprotein particles. Allows the net movement of cholesteryl esters from high density lipoproteins/HDL to triglyceride-rich very low density lipoproteins/VLDL, and the equimolar transport of triglyceride from VLDL to HDL (Drayna et al. 1987; Morton and Izem 2014). Regulates reverse cholesterol transport, by which excess cholesterol is removed from peripheral tissues and returned to the liver for elimination (Qiu et al. 2007).

Eukaryota
Metazoa
CETP of Homo sapiens
*1.C.40.2.1









Takeout-like protein-1, To1, of 240 aas and 1 N-terminal TMS.  Takeout proteins are insect juvenile hormone-binding proteins and arthropod allergens, which transport lipid hormones to target tissues during insect development (Alva and Lupas 2016).

Eukaryota
Metazoa
To1 of Epiphyas postvittana (Light brown apple moth)
*1.C.40.2.2









Takeout-like protein, To3 of 261 aas and 1 N-terminal TMS

Eukaryota
Metazoa
To3 of Danaus plexippus (Monarch butterfly)