TCDB is operated by the Saier Lab Bioinformatics Group
TCIDNameDomainKingdom/PhylumProtein(s)
*1.C.72.1.1









Pertussis toxin
Bacteria
Proteobacteria
Pertussis toxin of Bordetella pertussis A (S1) + B (S2-S5)
Subunit S1 (P04977)
Subunit S2 (P04978)
Subunit S3 (P04979)
Subunit S4 (P0A3R5)
Subunit S5 (P04981)
*1.C.72.2.1









The ADP-ribosyltransferase toxin, ArtAB (Saitoh et al., 2005) (ArtA but not ArtB is demonsratively homologous to subunits in pertussis toxin)
Bacteria
Proteobacteria
ArtAB of Salmonella enterica serovar Typhimurium
ArtA (Q404H4)
ArbB (Q404H3)
*1.C.72.3.1









The Subtilase cytotoxin, SubAB. Pentameric SubB, but not SubA, is homologous to ArtB of Salmonella enterica. SubA (AB5 subtilase) cytotoxin inactivates the endoplasmic reticulum chaperone, BiP (Paton et al., 2006; Beddoe et al., 2010).

Bacteria
Proteobacteria
Subtilase cytotoxin AB (SubAB) of E. coli
Subtilase A (Q3ZTX7)
Subtilase B (Q3ZTX8)
*1.C.72.4.1









Heat labile enterotoxin AB, EltAB, ItpAB, ToxAB, LT-AB (258 aas and 124 aas, respectively). The biological activity of the toxin is produced by the A chain, which activates intracellular adenyl cyclase. The A2 domain of LTA has cell penitration function (Liu et al. 2016). LT holotoxin can enter intestinal epithelial cells and cause diarrhea. The A2 domain might be useful as a transport vehicle for other proteins (Liu et al. 2016).

Bacteria
Proteobacteria
EltAB of E. coli 078:H11
*1.C.72.4.2









Heat labile enterotoxin IIB, A (α)-chain of 685 aas/B chain of

Bacteria
Spirochaetes
Enterotoxin of Leptospira borgpetersenii