TCDB is operated by the Saier Lab Bioinformatics Group
TCIDNameDomainKingdom/PhylumProtein(s)
*1.C.75.1.1









The Serratia pore-forming hemolysin/toxin of 1608 aas, ShlA. ShlA expression allows Serratia to trigger a Ca2+ signal that reshapes cytoskeleton dynamics and ends up pushing the Serratia-containing vacuoles out of the cell in an exocytic-like process (Di Venanzio et al. 2016). Thus, pore-forming toxins can allow bacteria to exit without compromising host cell integrity. ShlA triggers cadherin cleavage by promoting calcium influx which activates ADAM10 for proteolysis (Reboud et al. 2017).

Bacteria
Proteobacteria
ShlA of Serratia marcescens (P15320)
*1.C.75.1.2









Haemolysin of 3456 aas

Bacteria
Proteobacteria
Haemolysin of Enterobacter agglomerans (Erwinia herbicola) (Pantoea agglomerans)
*1.C.75.1.3









Haemagglutinin of 2521 aas

Bacteria
Proteobacteria
Haemagglutinin of Pseudomonas aeruginosa
*1.C.75.1.4









Filamentous hemagglutinin protein of 1599 aa

Bacteria
Proteobacteria
Filamentous hemagglutinin of Neisseria meningitidis
*1.C.75.1.5









Haemolysin XhlA of 1470 aas with 1 N-terminal TMS (Cowles and Goodrich-Blair 2005).

Bacteria
Proteobacteria
XhlA of Xenorhabdus nematophila (Achromobacter nematophilus)
*1.C.75.1.6









Exotoxin, ChlA of 1628 aas (Brumbach et al. 2007).

Bacteria
Proteobacteria
*1.C.75.1.7









Filamentous haemagglutinin family outer membrane protein of 2818 aas.

Bacteria
Proteobacteria
Haemagglutinin of Burkholderia ambifaria