TCDB is operated by the Saier Lab Bioinformatics Group
TCIDNameDomainKingdom/PhylumProtein(s)
*1.C.85.1.1









β-defensin-1
Eukaryota
Metazoa
β-defensin-1 of Homo sapiens (P60022)
*1.C.85.1.2









β-defensin-2
Eukaryota
Metazoa
β-defensin 2 of Homo sapiens (O15263)
*1.C.85.1.3









β-defensin-3
Eukaryota
Metazoa
β-defensin-3 of Homo sapiens (P81534)
*1.C.85.1.4









β-defensin-14
Eukaryota
Metazoa
β-defensin-14 of Mus musculus (Q7TNV9)
*1.C.85.1.5









Epididymus sperm-associated antigen (EP2E)

Eukaryota
Metazoa
EP2E of Homo sapiens (Q9H4P9)
*1.C.85.1.6









β-defensin-2 of 71 aas and 1 TMS

Eukaryota
Metazoa
Defensin β2 of Mus musculus
*1.C.85.1.7









β-defensin 11 of 69 aas and 1 TMS

Eukaryota
Metazoa
Defb11 of Rattus norvegicus
*1.C.85.1.8









beta-Defensin 3 of 63 aas and 1 TMS (Colavita et al. 2015).  Sass et al. have proposed that interference with the organisation of membrane-bound multienzyme complexes such as the electron transport chain and the cell wall biosynthetic complex rather than on formation of defined transmembrane pores is responsible for death of Staphylococcus aureus (Sass et al. 2008).

Eukaryota
Metazoa
BD3 pf Mus musculus
*1.C.85.2.1









Myotoxin-4 or Crotamine-4. Specifically modifies voltage-sensitive Na+ channels and exhibits analgesic effects. Belongs to the snake myotoxin family.

Eukaryota
Metazoa
Myotoxin-4 of Crotalus durissus terrificus (P24334)
*1.C.85.2.2









Crotamine-IV-2 toxin of 42 aas and 0 TMSs

Eukaryota
Metazoa
Croamine-IV-2 of Crotalus durissus cumanensis
*1.C.85.2.3









β-defensin-like protein of 63 aas and 1 TMS

Eukaryota
Metazoa
defensin-like protein of Bothrops matogrossensis (Pitviper) (Bothrops neuwiedi matogrossensis)
*1.C.85.2.4









Crotamine-like precursor of 76 aas and 1 TMS.

Eukaryota
Metazoa
Crotamine-like peptide of Thamnodynastes strigatus (Coastal house snake)
*1.C.85.3.1









Epithelial Gallinacin-1α. The full length antimicrobial peptide precursor is CHP2. Attacks bacteria and fungi. 

Eukaryota
Metazoa
Gallinacin 1α of Gallus gallus (P46157)
*1.C.85.3.2









β-defensin prepropeptide of 59 aas and 2 TMSs.

Eukaryota
Metazoa
β-defensin of Meleagris gallopavo (turkey)
*1.C.85.3.3









Avian beta-defensin, 5beta of 66 aas and 1 TMS.
Eukaryota
Metazoa
Beta-defensin of Columba livia (domestic pigeon)
*1.C.85.4.1









Helofensin-1 lethal toxin of 183 aas (PMID 19837656).  This toxin possesses an inhibitory effect on electrical stimulation of the isolated hemi-diaphragm of mice. Neither hemorrhagic nor hemolytic activities were detected, but Huang et al. 2016 reported it to be a membrane active protein.

Eukaryota
Metazoa
Helofensin-1 of Heloderma suspectum cinctum (Banded Gila monster)
*1.C.85.4.2









Helofensin-3 (90% identical to helofensin-1) of 182 aas.  A lethal toxin.

Eukaryota
Metazoa
Helofensin-3 of Heloderma suspectum cinctum (Banded Gila monster)
*1.C.85.4.3









Uncharacterized protein of 172 aas

Eukaryota
Metazoa
UP of Nematostella vectensis (Starlet sea anemone)