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1.C.85.2.1
Myotoxin-4 or Crotamine-4. Specifically modifies voltage-sensitive Na+ channels and exhibits analgesic effects. Belongs to the snake myotoxin family.

Accession Number:P24334
Protein Name:Myotoxin-4
Length:51
Molecular Weight:5933.00
Species:crotalus durissus terrificus (South American rattlesnake) [8732]
Location1 / Topology2 / Orientation3: Secreted1
Substrate small molecules

Cross database links:

Pfam: PF00819   

Gene Ontology

GO:0005576 C:extracellular region
GO:0019871 F:sodium channel inhibitor activity
GO:0009405 P:pathogenesis

References (1)

[1] “Cloning and nucleotide sequences of crotamine genes.”  Smith L.A.et.al.   2389256

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	FLSEPGNAYK QCHKKGGHCF PKEKICIPPS SDFGKMDCRW RWKCCKKRSG K