TCDB is operated by the Saier Lab Bioinformatics Group

1.D.82.  The Electroporation-genetrated Pore (EgP) Family 

The applications of nanosecond, megavolt-per-meter electric field pulses to biological systems show cellular and subcellular electric field induced effects of electroporation. The absolute rate theory, with experimentally based parameter input, is consistent with membrane pore creation on a nanosecond time scale. Use of a Smoluchowski equation-based model for a planar cell membrane patch exposed to a 10 ns trapezoidal pulse with 1.5 ns rise and fall times, reversible supraelectroporation behavior in terms of transmembrane voltage, pore density, membrane conductance, fractional aqueous area, pore distribution, and average pore radius has been determined (Vasilkoski et al. 2006). Pore creation dominates the electrical response, and pore expansion prived to be negligible on this ns time scale.

References associated with 1.D.82 family:

Vasilkoski, Z., A.T. Esser, T.R. Gowrishankar, and J.C. Weaver. (2006). Membrane electroporation: The absolute rate equation and nanosecond time scale pore creation. Phys Rev E Stat Nonlin Soft Matter Phys 74: 021904. 17025469