1.D.84. The Aromatic Helical Origomeric Channel (AHOC) Family
Chao et al. 2017 synthesized aromatic helical oligomeric compounds that selectively bind K+ over Na+. By aromatic stacking of helical oligomers, artificial K+ channels with contiguous K+ binding sites were constructed. These artificial channels exhibited exceptionally high K+/Na+ selectivity ratios during transmembrane ion conduction.