TCDB is operated by the Saier Lab Bioinformatics Group
TCIDNameDomainKingdom/PhylumProtein(s)
*1.E.11.1.1









Holin 145 (Bon et al. 1997)

Viruses
Caudovirales
Holin (145 aas)
*1.E.11.1.2









Holin
Viruses
Caudovirales
Holin (88 aas)
*1.E.11.1.3









Holin of 85 aas, Ejh (Diaz et al. 1996).  A synthetic peptide based on Ejh has been reconstituted and shown to be active (Haro et al. 2003).  Ejh has been used to promote release of polyhydroxyalkanoate granules from bacterial cells (Martínez et al. 2011).

Viruses
Caudovirales
Holin EJh (85 aas)
*1.E.11.1.4









Holin

Bacteria
Firmicutes
Holin of of Streptococcus pyongenes
*1.E.11.1.5









Holin HolTW (Loessner et al. 1998).

Viruses
Caudovirales
Holin HolTS of Staphylococcus phage TWORT
*1.E.11.1.6









Putative holin

Bacteria
Firmicutes
Putative holin of Listeria innocua
*1.E.11.1.7









Putative holin; phage phiLC3 holin family

Bacteria
Firmicutes
Putative holin of Streptococcus sanguinis
*1.E.11.1.8









Holin (Orf33) of 167 aas from Stahylococcus phage K. Phage K lysis differentially affects planctonic and biofilm cells (Cerca et al. 2007; Curtin and Donlan 2006).  95% identical to HolGH15 of phage GH15 of S. aureus which has broad host range antibacterial activity against many pathogens (Song et al. 2016).

Viruses
Caudovirales
Orf33 of Stahylococcus phage K; HolGH15 of Staphylococcus phage GH15
*1.E.11.1.9









Holin of the phage phi LC3 family of 91 aas and 2 TMSs

Bacteria
Actinobacteria
Holin of Collinsella aerofaciens
*1.E.11.1.10









Holin of 100 aas and 2 TMSs

Bacteria
Actinobacteria
Holin of Atopobium parvulum
*1.E.11.2.1









Holin of Clostridium phage phiCP390 (Seal et al. 2011).  This holin is identical to the holin of phage phiCP26F (gp23; F2VHY0).

Viruses
Caudovirales
Holin of Clostridium perfringens phage PhiCP390
*1.E.11.2.2









Putative holin

Bacteria
Firmicutes
Putative holin of Clostridium perfringens
*1.E.11.2.3









Putative holin

Bacteria
Firmicutes
Putative holin of Geobacillus kustophilus
*1.E.11.3.1









Putative holin of 49 aas and 1 TMS.  TMS 1 corresponds to TMS 2 in the holins of TC subfamilies 1.E.11.1 and 1.E.11.2.

Bacteria
Proteobacteria
Putative holin of Pseudomonas putida
*1.E.11.3.2









Putative holin of 50 aas and 1 TMS

Bacteria
Proteobacteria
Putative holin of Pseudomonas syringae