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1.N.4.1.1
EFF-1A of 658 aas and 2 TMSs, N- and C-terminal.  Required for normal cell fusion. The EFF-1A endodomain is required for normal rates of EFF-1-dependent epidermal cell fusions (Shinn-Thomas et al. 2016).

Accession Number:G5ECA1
Protein Name:EFF-1A
Length:658
Molecular Weight:74401.00
Species:Caenorhabditis elegans [6239]
Number of TMSs:1
Substrate small molecules, macromolecules

Cross database links:

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MEPPFEWSPQ FILLLLAVTT YGFPLEEKFD GLFRAEPPHC SKTPIVRAQT SQNAMSSIAR 
61:	GMQMQFSIGL HTAVCFRLYE DTQLASQEIN DDENAGNQTS LLHTIRLEKL EHHHPITQRY 
121:	TFGIPEVHAS CICECDATSS TCTAESHQFT ACPESDKSDE TSSCYRTFFP NQTPIGCSED 
181:	DIPKLCCDVR FKPYKNMTFL AVKLEQPTTY ATFVYAAYDF VNGYWVEKDK TKIRSQLDGG 
241:	TQDRHLDQKR RISLAVTAGG RASHQLETGM YFSRTSNGGE TEELRMQPLN EITDNNFDRL 
301:	GWYRMDDSGH FHVNNGVVKM DDIHKAKVKN CKEQTYKSIL SANHYMPGHF NLTRPLEVIK 
361:	PWIQSARIFD SSLRQAVVTH AEGTNLQISI HLDDEVESQN LVFFHNASRI RDFSGSIIVD 
421:	SKSNRLFNLT VYEASGKIDG SVKMSTGFGS DTIHTFTAYV SDLHASNRSM IIPLPAIVGQ 
481:	GARAICLRAD SMADIDKICH VIEYFESPLE IDLVEGKWHE MIGTCPTCNQ INFNGMMKFL 
541:	NPAHWIKGIS SIGDGVMIAT DIVVYLGVLC ILYLLITKII VPLVRCWVCP MSIFCNGSSS 
601:	SSKNKNDKRR KEREERRRKD KFVSESEDGA RSSSEPHDTL ARYHGNHSER HYSSSQYI