2.A.101 The Malonate Uptake (MatC) Family (Formerly UIT1)
The UIT1 family is a constituent of the IT superfamily (Lolkema and Slotboom, 2003; Prakash et al., 2003; Rabus et al., 1999). It is the st308/DctB family of Lolkema and Slotboom (2003). It consists of proteins from Gram-negative and Gram-positive bacteria (e.g., Xanthomonas, Rhizobium and Streptomyces species). The proteins are of about 450 aas with 12-14 putative TMSs. Closest functionally-characterized homologues are in the DASS (TC #2.A.47) family. One member of this family is a putative malonate transporter (An and Kim, 1998).
MatC is a part of the IT superfamily.