TCDB is operated by the Saier Lab Bioinformatics Group
« See all members of the family


2.A.14.1.3
L-lactate permease

Accession Number:P71067
Protein Name:L-lactate permease
Length:563
Molecular Weight:59762.00
Species:Bacillus subtilis (strain 168) [224308]
Number of TMSs:16
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate L-lactate

Cross database links:

eggNOG: COG1620
HEGENOM: HOG000253321
Entrez Gene ID: 936322   
Pfam: PF02652   
KEGG: bsu:BSU34190   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0015129 F:lactate transmembrane transporter activity
GO:0035873 P:lactate transmembrane transport

References (3)

[1] “The complete genome sequence of the Gram-positive bacterium Bacillus subtilis.”  Kunst F.et.al.   9384377
[2] “Integrated mapping and sequencing of a 115 kb DNA fragment from Bacillus subtilis: sequence analysis of a 21 kb segment containing the sigL locus.”  Fabret C.et.al.   8969506
[3] “A widely conserved gene cluster required for lactate utilization in Bacillus subtilis and its involvement in biofilm formation.”  Chai Y.et.al.   19201793

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
Window Size: Angle:  
FASTA formatted sequence
1:	MQWTQAYTPI GGNLLLSALA ALVPIIFFFW ALAIKRMKGY TAGLATLGIA LIIAVLVYRM 
61:	PAEKALMSAT QGAVYGLLPI GWIIVTSVFL YKITVKTGQF DIIRSSVLSI TDDRRLQALL 
121:	IAFSFGAFLE GAAGFGAPVA ISAALLVGLG FNPLYAAGIC LIANTAPVAF GAIGIPITAV 
181:	EGPTGIPAME ISQMVGRQLP FLSVFIPLYL IIIMSGFRKA LEIWPAILVS GVSFAVVQYL 
241:	SSNFLGPELP DVLSALVSMA ALAVFLKWWK PKTTFRFAGE QESAASIETA RTNPAAPAYR 
301:	GGQIFKAWSP FLLLTAMISV WGIPSVKSAL TGHYEGSAVF LKWLNAVGEK LTFSPGVPFL 
361:	NNQIVNADGT PIEAVYKLEV LGSAGTAILI AAVLSKFITA ISWKDWGTVF KETVQELKLP 
421:	ILTIASVVGF AYVTNSSGMS TTLGMTLALT GSMFTFFSPV LGWLGVFITG SDTSANLLFG 
481:	NLQKVTALSV GMDPVLSVAA NSSGGVTGKM ISPQSIAVAC AAVGLAGKES DLFRFTIKHS 
541:	LFLLLLVCII TFLQHHVFSW MIP