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2.A.14.1.4
Putative transporter

Accession Number:Q8TUV1
Protein Name:L-lactate permease
Length:466
Molecular Weight:49375.00
Species:Methanopyrus kandleri [2320]
Number of TMSs:13
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate Unknown

Cross database links:

RefSeq: NP_614935.1   
Entrez Gene ID: 1478247   
Pfam: PF02652   
BioCyc: MKAN190192:MK1652-MONOMER   
KEGG: mka:MK1652   

Gene Ontology

GO:0015129 F:lactate transmembrane transporter activity
GO:0015727 P:lactate transport

References (1)

[1] “The complete genome of hyperthermophile Methanopyrus kandleri AV19 and monophyly of archaeal methanogens.”  Slesarev A.I.et.al.   11930014

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MRLYRRRDPE PQSPSSSEGG LPLPSLALVV PLISISALIV AALRGWGLFR ASSLSLALYL 
61:	IASTFTPFTV QVPYVRVVDS ALKGVEILAV VLASLTLVEM MREDGVLEDI VHILKETCQL 
121:	RGPCLVGLSV VATGAFESVA SFGTPATLVG PLLVEAGLSK TTAAAAALVG HAPFGVFAAF 
181:	GVPILVTSGV SGIDPKKLSF DVALCIAPSL LVLPYAVAET ADLRVSKVLL TTMGIMTTAS 
241:	LLAVWWVASP SIVGPLLVLG VASGFLWYLR VAGEEARIKV SNDTIKGMIV YGLVVVGIGV 
301:	VKALDVKWVQ PWMLLWVAVL LYATPRWTRM VGALIRVLRK TWEELLSIVL LMVLGTLIAH 
361:	SELPSAIRPY AGSPLVTFLV GFMGEMVVGS TTAVMATFAS GTPYPEITLA GAACAAAACP 
421:	YNVAVAAAAV RCHEKRVMRR SLLGSMYLTV PTLAWCTMLW IWGAMK