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2.A.24.2.1
L-Malate permease

Accession Number:Q53787
Protein Name:MaeP aka MALP
Length:441
Molecular Weight:47222.00
Species:Streptococcus bovis [1335]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate L-malate

Cross database links:

Pfam: PF03390   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0008514 F:organic anion transmembrane transporter act...
GO:0015711 P:organic anion transport

References (1)

[1] “Purification and characterization of a malic enzyme from the ruminal bacterium Streptococcus bovis ATCC 15352 and cloning and sequencing of its gene.”  Kawai S.et.al.   8702261

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MEKKLPATAA NETDWRNKLT KTRIGSVTLP VYLVTASIIL VTALLEQLPV NMLGGFAVIL 
61:	TMGWLLGTIG GNIPILKHFG GPAILSLLVP SIMVFFNLLN QNVLDSTDIL MKQANFLYFY 
121:	IACLVCGSIL GMNRKILVQG LMRMIVPMAL GMILAMGVGT LVGTLLGLGW KHSLFYIVTP 
181:	VLAGGIGEGI LPLSLGYSAI TGLPSEQLVG QLIPATIIGN FFAIMCSGLL SRLGEKRPEL 
241:	SGQGQLIKIT NSDDLSDALE EDKAPIDVKL MGAGVLIACT LFITGGLLQH LTGFPGPVLM 
301:	IVVAAFLKYL NVVPKETQRG SKQLYKFISG NFTFPLMVGL GMLYIPLKDV VGMLSWQYFV 
361:	VVISVVFTVI ATGFFVSRFM NMNPVEAAIV SACQSGMGGT GDVAILSTAN RMTLMPFAQV 
421:	ATRLGGAITV ITMTAIFRML F