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2.A.24.2.2
Malate:lactate antiporter (substrates include: S-lactate, R-lactate, S-malate and S-citramalate)

Accession Number:O07032
Protein Name:MaeP aka MLEP aka LL0901
Length:425
Molecular Weight:45309.00
Species:Lactococcus lactis (subsp [1360]
Number of TMSs:13
Location1 / Topology2 / Orientation3: Cell outer membrane1
Substrate malate, Lactate, Citramalate

Cross database links:

HEGENOM: HBG304840
RefSeq: NP_267057.1   
Entrez Gene ID: 1114531   
Pfam: PF03390   
BioCyc: LLAC272623:L123159-MONOMER   
KEGG: lla:L123159   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0008514 F:organic anion transmembrane transporter act...
GO:0015711 P:organic anion transport

References (1)

[1] “The complete genome sequence of the lactic acid bacterium Lactococcus lactis ssp. lactis IL1403.”  Bolotin A.et.al.   11337471

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
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FASTA formatted sequence
1:	MKKLKETKIS GISLPLYAFF VAVIIVVTLL GKLPLDMVGL TLLLVTLGHL LYFIGEKFPI 
61:	MNSYLGGGSV FTLIGATLLS FFHIVPSNVI GAVSNFMGGK FGFLDFYIAA LICGSILGMN 
121:	RNLLVKASKK FIPIALITMV IGFFSVGLVG MLIGNGFADS VMYVSMPMMS GGMGAGITPL 
181:	SQIYAAGLAH GNQAAIFSQL APAVTFGNIL AIIGALSIAK VFNKSKYNGH GTLVAATKEE 
241:	LAKPKIKLDA QQIGTGMLFA FALLMAGDIL NKFFPNIHQY AFMIIIVFIL KATNTVPKDL 
301:	EESVVMFNQV IMTNLTHAVL AGIGLALIDL NTLASAFTWQ FVVLCLTSVV VMGLASWFLA 
361:	RLFGLYPVET AIGAGMINNS MGGTGNIAVL SASDRMEMIA FAQMANRLCG AIVLIFGGIL 
421:	IRFFY