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2.A.24.2.4
L-malate/citrate:H+ symporter (electroneutral)

Accession Number:P94363
Protein Name:CimH aka YxkJ
Length:450
Molecular Weight:48339.00
Species:Bacillus subtilis [1423]
Number of TMSs:11
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate L-malate, Citrate, H+

Cross database links:

HEGENOM: HBG304840
RefSeq: NP_391756.1   
Entrez Gene ID: 937407   
Pfam: PF03390   
KEGG: bsu:BSU38770   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0008514 F:organic anion transmembrane transporter act...
GO:0015293 F:symporter activity
GO:0006101 P:citrate metabolic process
GO:0015711 P:organic anion transport

References (3)

[1] “Sequencing of a 65 kb region of the Bacillus subtilis genome containing the lic and cel loci, and creation of a 177 kb contig covering the gnt-sacXY region.”  Yoshida K.et.al.   8969509
[2] “The complete genome sequence of the Gram-positive bacterium Bacillus subtilis.”  Kunst F.et.al.   9384377
[3] “Bacillus subtilis YxkJ is a secondary transporter of the 2-hydroxycarboxylate transporter family that transports L-malate and citrate.”  Krom B.P.et.al.   11566984

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MGELQTHMQL QTDTIHEGVR KENWFAKAMN IKVGIIPLPV YALLFILITV FVMHHDVKSD 
61:	ILTSIAVMAF FGFTFAQIGK SIPIVRSIGG PAILATFIPS AVVYYHLLPN DIVKSTTEFT 
121:	ENSNFLYLFI AGIVVGSILG MKRETLVKAF MKIFIPLIVG SVTAAIVGLA VGTLLGLGFQ 
181:	HTLLYIVIPI MAGGVGEGAI PLSIGYSDIM PISQGEAFAL VLPSIMLGSL CAIILAGLLN 
241:	RIGKKKPEWT GNGKVDRSEE ESPALEESQS GQQMFNLSLF ASGGILAVSL YLVGMLAHDF 
301:	FGFPAPVAML LLAVLIKLFR LVPASIENGA FGVSRFFSTA VTYPLLFAIG VSMTPWDKLV 
361:	AAFNLSNIIT ILSVVVTMMA VGFFTGKWLN MYPIETAIIN ACHSGQGGTG DVAILSAAER 
421:	LELMPFAQVS TRIGGAITVS LTLLLLHQFY