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2.A.3.11.1
The aspartate uptake permease, YveA (also transports L-aspartate hydroxamate and glutamate, and possibly asparagine and glutamine; Lorca et al., 2003)

Accession Number:O07002
Protein Name:YveA
Length:520
Molecular Weight:56989.00
Species:Bacillus subtilis [1423]
Number of TMSs:14
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate aspartate, glutamate, L-aspartate hydroxamate

Cross database links:

HEGENOM: HBG710413
RefSeq: NP_391327.1   
Entrez Gene ID: 938612   
Pfam: PF00324   
BioCyc: SUBTI:BSU34470-MONOMER   
KEGG: bsu:BSU34470   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0015171 F:amino acid transmembrane transporter activity
GO:0015293 F:symporter activity
GO:0006865 P:amino acid transport
GO:0055085 P:transmembrane transport

References (3)

[1] “The complete genome sequence of the Gram-positive bacterium Bacillus subtilis.”  Kunst F.et.al.   9384377
[2] “yveB, encoding endolevanase LevB, is part of the sacB-yveB-yveA levansucrase tricistronic operon in Bacillus subtilis.”  Pereira Y.et.al.   11739774
[3] “Identification of the L-aspartate transporter in Bacillus subtilis.”  Lorca G.et.al.   12730183

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MSKQGNFQKS MSLFDLILIG MGAIFGSAWL FAVSNVASKA GPSGAFSWIL GGAIILLIGL 
61:	VYAELGAALP RTGGIIRYPV YSHGHLVGYL ISFVTIVAYT SLISIEVTAV RQYVAYWFPG 
121:	LTIKGSDSPT ISGWILQFAL LCLFFLLNYW SVKTFAKANF IISIFKYIVP ITIIIVLIFH 
181:	FQPENLSVQG FAPFGFTGIQ AAISTGGVMF AYLGLHPIVS VAGEVQNPKR NIPIALIICI 
241:	IVSTIIYTVL QVTFIGAIPT ETLKHGWPAI GREFSLPFKD IAVMLGLGWL ATLVILDAIL 
301:	SPGGNGNIFM NTTSRLVYAW ARNGTLFGIF SKVNKDTGTP RASLWLSFAL SIFWTLPFPS 
361:	WNALVNVCSV ALILSYAIAP ISSAALRVNA KDLNRPFYLK GMSIIGPLSF IFTAFIVYWS 
421:	GWKTVSWLLG SQLVMFLIYL CFSKYTPKED VSLAQQLKSA WWLIGFYIMM LIFSYIGSFG 
481:	HGLGIISNPV DLILVAIGSL AIYYWAKYTG LPKAAIDYDK