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2.A.3.2.7
Arginine/agmatine antiporter

Accession Number:Q9Z6M8
Protein Name:Arginine/agmatine antiporter
Length:485
Molecular Weight:52548.00
Species:Chlamydia pneumoniae [83558]
Number of TMSs:13
Location1 / Topology2 / Orientation3: Cell inner membrane1 / Multi-pass membrane protein2
Substrate Arginine

Cross database links:

eggNOG: COG0531
HEGENOM: HOG000164505
Entrez Gene ID: 1467750    894716    919805    962779   
KEGG: cpa:CP0821    cpj:CPj1031    cpn:CPn1031    cpt:CpB1071   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0015171 F:amino acid transmembrane transporter activity
GO:0015297 F:antiporter activity
GO:0009405 P:pathogenesis

References (4)

[1] “Comparative genomes of Chlamydia pneumoniae and C. trachomatis.”  Kalman S.et.al.   10192388
[2] “Genome sequences of Chlamydia trachomatis MoPn and Chlamydia pneumoniae AR39.”  Read T.D.et.al.   10684935
[3] “Comparison of whole genome sequences of Chlamydia pneumoniae J138 from Japan and CWL029 from USA.”  Shirai M.et.al.   10871362
[4] “Outer and inner membrane proteins compose an arginine-agmatine exchange system in Chlamydophila pneumoniae.”  Smith C.B.et.al.   18790867

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MTSRTKSSKN LGTIALAGMV VSSIIGGGIF SLPQNMAATA GAGAVILSWI LTGFGMFFIA 
61:	NTFRILSTIR PDLKEGIYMY SREGFGPYIG FTIGWGYWLC QIFGNVGYAV ITMDALNYFF 
121:	PPYFQGGNTL PAILGGSILI WVFNFIVLKG IRQASIINVI GTIFKIIPLI IFIILTAFFF 
181:	KLAVFKTDFW GHAVTKAQPS LGSVSSQLKG TMLVTLWAFI GIEGAVVMSG RAKNPLSVGQ 
241:	ATVLGFLGCL TIYILFSLLP FGSLFQHQLA NIPNPSTAGV LDILVGKWGE VLMNVGLIIA 
301:	VLSSWLSWTI IVAEIPFSAA KNGTFPEIFT IENKEKSPSV SLYITSSVMQ LAMLLVYFSS 
361:	NAWNTMLSIT GVMVLPAYLA SAAFLFKLSK SKTYPKKGSI KAPLAMITGI LGVVYSLWLI 
421:	YAGGLKYLFM ALVLLALGIP FYIDAGKKKK NAKTFFAKKE IVGMTFIGLL ALTAIFLFST 
481:	GRIKI