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2.A.3.2.8
Putative arginine/ornithine antiporter

Accession Number:P0AAE5
Protein Name:Putative arginine/ornithine antiporter
Length:460
Molecular Weight:49501.00
Species:Escherichia coli (strain K12) [83333]
Number of TMSs:13
Location1 / Topology2 / Orientation3: Cell inner membrane1 / Multi-pass membrane protein2
Substrate Arginine

Cross database links:

Genevestigator: P0AAE5
EchoBASE: EB3689
EcoGene: EG13930
eggNOG: COG0531
HEGENOM: HOG000164505
DIP: DIP-48049N
Entrez Gene ID: 945159   
KEGG: eco:b1605   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0015171 F:amino acid transmembrane transporter activity
GO:0015297 F:antiporter activity

References (4)

[1] “A 570-kb DNA sequence of the Escherichia coli K-12 genome corresponding to the 28.0-40.1 min region on the linkage map.”  Aiba H.et.al.   9097039
[2] “The complete genome sequence of Escherichia coli K-12.”  Blattner F.R.et.al.   9278503
[3] “Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110.”  Hayashi K.et.al.   16738553
[4] “Global topology analysis of the Escherichia coli inner membrane proteome.”  Daley D.O.et.al.   15919996

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MEKKLGLSAL TALVLSSMLG AGVFSLPQNM AAVASPAALL IGWGITGAGI LLLAFAMLIL 
61:	TRIRPELDGG IFTYAREGFG ELIGFCSAWG YWLCAVIANV SYLVIVFSAL SFFTDTPELR 
121:	LFGDGNTWQS IVGASALLWI VHFLILRGVQ TAASINLVAT LAKLLPLGLF VVLAMMMFKL 
181:	DTFKLDFTGL ALGVPVWEQV KNTMLITLWV FIGVEGAVVV SARARNKRDV GKATLLAVLS 
241:	ALGVYLLVTL LSLGVVARPE LAEIRNPSMA GLMVEMMGPW GEIIIAAGLI VSVCGAYLSW 
301:	TIMAAEVPFL AATHKAFPRI FARQNAQAAP SASLWLTNIC VQICLVLIWL TGSDYNTLLT 
361:	IASEMILVPY FLVGAFLLKI ATRPLHKAVG VGACIYGLWL LYASGPMHLL LSVVLYAPGL 
421:	LVFLYARKTH THDNVLNRQE MVLIGMLLIA SVPATWMLVG